INT242151

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Context Info
Confidence 0.36
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.31
Pain Relevance 0.03

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Wnt2) molecular_function (Wnt2) cell-cell signaling (Wnt2)
cytoplasm (Wnt2)
Wnt2 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Hippocampus 3 60.64 Quite High
Central nervous system 6 24.32 Low Low
Kinase C 13 5.00 Very Low Very Low Very Low
agonist 9 5.00 Very Low Very Low Very Low
depression 6 5.00 Very Low Very Low Very Low
cINOD 4 5.00 Very Low Very Low Very Low
Inflammation 4 5.00 Very Low Very Low Very Low
Nicotine 3 5.00 Very Low Very Low Very Low
Pyramidal cell 1 5.00 Very Low Very Low Very Low
nMDA receptor 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Toxicity 7 92.56 High High
Drug Induced Neurotoxicity 12 34.88 Quite Low
Disease 61 24.56 Low Low
Apoptosis 13 12.00 Low Low
Neurodegenerative Disease 10 5.00 Very Low Very Low Very Low
Targeted Disruption 7 5.00 Very Low Very Low Very Low
Depression 6 5.00 Very Low Very Low Very Low
Amyloid Plaque 6 5.00 Very Low Very Low Very Low
Alzheimer's Dementia 5 5.00 Very Low Very Low Very Low
INFLAMMATION 5 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
-catenin degradation, these Wnt-3a effects are potentiated by over-expression of Fz1, but not Fz2, and are significantly reduced when Fz1 is knocked down by antisense oligonucleotides in PC12 cells [92].
Negative_regulation (reduced) of Protein_catabolism (degradation) of Wnt
1) Confidence 0.36 Published 2008 Journal Mol Neurodegener Section Body Doc Link PMC2515306 Disease Relevance 0.31 Pain Relevance 0.03

General Comments

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