INT242154

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Context Info
Confidence 0.35
First Reported 2008
Last Reported 2010
Negated 0
Speculated 1
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.89
Pain Relevance 0.30

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Wnt2) molecular_function (Wnt2) cell-cell signaling (Wnt2)
cytoplasm (Wnt2)
Wnt2 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
agonist 9 99.80 Very High Very High Very High
antagonist 6 96.72 Very High Very High Very High
Inflammation 4 88.68 High High
cINOD 6 58.68 Quite High
metalloproteinase 1 12.80 Low Low
Kinase C 13 5.00 Very Low Very Low Very Low
Central nervous system 7 5.00 Very Low Very Low Very Low
depression 6 5.00 Very Low Very Low Very Low
Nicotine 3 5.00 Very Low Very Low Very Low
Hippocampus 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cancer 29 94.84 High High
INFLAMMATION 6 88.68 High High
Disease 62 83.36 Quite High
Diabetes Mellitus 2 83.08 Quite High
Insulin Resistance 1 77.64 Quite High
Carcinoma 13 63.52 Quite High
Apoptosis 19 58.32 Quite High
Neurodegenerative Disease 10 43.76 Quite Low
Stress 2 42.56 Quite Low
Lifespan 1 28.44 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
agonists modulate Wnt signaling components, including the inhibition of GSK-3?
Negative_regulation (inhibition) of Gene_expression (components) of Wnt associated with agonist
1) Confidence 0.35 Published 2008 Journal Mol Neurodegener Section Body Doc Link PMC2515306 Disease Relevance 0.55 Pain Relevance 0.13
In addition, small interference of RNA (siRNA) may eliminate components of Wnt/?
Spec (may) Negative_regulation (eliminate) of Gene_expression (/) of Wnt
2) Confidence 0.05 Published 2010 Journal J Hematol Oncol Section Body Doc Link PMC2954871 Disease Relevance 0.34 Pain Relevance 0.17

General Comments

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