INT242156

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Context Info
Confidence 0.42
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 3
Disease Relevance 0.23
Pain Relevance 0.34

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Wnt2) molecular_function (Wnt2) cell-cell signaling (Wnt2)
cytoplasm (Wnt2)
Anatomy Link Frequency
intestine 4
Wnt2 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Kinase C 13 95.64 Very High Very High Very High
agonist 9 5.00 Very Low Very Low Very Low
Central nervous system 6 5.00 Very Low Very Low Very Low
depression 6 5.00 Very Low Very Low Very Low
dexamethasone 4 5.00 Very Low Very Low Very Low
cINOD 4 5.00 Very Low Very Low Very Low
Inflammation 4 5.00 Very Low Very Low Very Low
Nicotine 3 5.00 Very Low Very Low Very Low
Hippocampus 3 5.00 Very Low Very Low Very Low
anesthesia 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Drug Induced Neurotoxicity 12 89.36 High High
Apoptosis 15 69.44 Quite High
Disease 61 67.84 Quite High
Amyloid Plaque 6 46.76 Quite Low
Targeted Disruption 7 40.72 Quite Low
Alzheimer's Dementia 5 36.28 Quite Low
Manic Depressive Disorder 2 32.36 Quite Low
Neurodegenerative Disease 10 27.36 Quite Low
Cancer 2 23.92 Low Low
Toxicity 7 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
-catenin degradation and thus, activating the transcription of Wnt target genes such as engrailed and cyclin-D1.
Positive_regulation (activating) of Transcription (transcription) of Wnt
1) Confidence 0.42 Published 2008 Journal Mol Neurodegener Section Body Doc Link PMC2515306 Disease Relevance 0.23 Pain Relevance 0.34
In addition, it has been reported that glucocorticoid-induced transcription of Wnt occurs in the intestine of mice [1].
Positive_regulation (induced) of Transcription (transcription) of Wnt in intestine
2) Confidence 0.30 Published 2008 Journal Acta Histochemica et Cytochemica Section Body Doc Link PMC2532488 Disease Relevance 0 Pain Relevance 0
In addition, it has been reported that glucocorticoid-induced transcription of Wnt occurs in the intestine of mice [1].
Positive_regulation (occurs) of Transcription (transcription) of Wnt in intestine
3) Confidence 0.20 Published 2008 Journal Acta Histochemica et Cytochemica Section Body Doc Link PMC2532488 Disease Relevance 0 Pain Relevance 0

General Comments

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