INT242157

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Context Info
Confidence 0.37
First Reported 2008
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 1.08
Pain Relevance 0.11

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Wnt2) molecular_function (Wnt2) cell-cell signaling (Wnt2)
cytoplasm (Wnt2)
Anatomy Link Frequency
B cell 2
Wnt2 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Nicotine 3 89.76 High High
Central nervous system 7 57.12 Quite High
Inflammation 4 43.60 Quite Low
antagonist 6 41.88 Quite Low
agonist 9 26.40 Quite Low
Kinase C 13 5.00 Very Low Very Low Very Low
depression 6 5.00 Very Low Very Low Very Low
cINOD 6 5.00 Very Low Very Low Very Low
Hippocampus 3 5.00 Very Low Very Low Very Low
nMDA receptor 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Targeted Disruption 10 92.64 High High
Hematological Disease 4 90.64 High High
Familial Adenomatous Polyposis 55 89.76 High High
Disease 62 67.84 Quite High
Hematologic Neoplasms 11 60.76 Quite High
Cancer 60 51.92 Quite High
Apoptosis 24 50.40 Quite High
Colorectal Cancer 54 50.00 Quite Low
Amyloid Plaque 6 46.80 Quite Low
Hepatocellular Cancer 2 44.48 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
7-nAChR could be a target of the Wnt pathway by regulating the pre-synaptic localization of APC and ?
Regulation (target) of Localization (localization) of Wnt
1) Confidence 0.37 Published 2008 Journal Mol Neurodegener Section Body Doc Link PMC2515306 Disease Relevance 0.12 Pain Relevance 0.11
Wnt secretion is controlled by the Wntless/evenness transmembrane protein [58].
Regulation (controlled) of Localization (secretion) of Wnt
2) Confidence 0.09 Published 2008 Journal Current Genomics Section Body Doc Link PMC2674304 Disease Relevance 0.36 Pain Relevance 0
-catenin in hematopoietic stem cells blocks multilineage differentiation; including B cell differentiation at early stages, suggesting the importance of fine tuning of Wnt/?
Regulation (importance) of Localization (tuning) of Wnt in B cell
3) Confidence 0.05 Published 2010 Journal J Hematol Oncol Section Body Doc Link PMC2954871 Disease Relevance 0.59 Pain Relevance 0

General Comments

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