INT242168

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Context Info
Confidence 0.67
First Reported 2008
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 4
Total Number 4
Disease Relevance 1.17
Pain Relevance 0.46

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (JUP) cell morphogenesis (JUP) structural molecule activity (JUP)
plasma membrane (JUP) cytoskeleton (JUP) nucleus (JUP)
Anatomy Link Frequency
muscle 1
JUP (Homo sapiens)
Pain Link Frequency Relevance Heat
agonist 9 94.32 High High
Inflammation 5 83.40 Quite High
bDMF 16 79.92 Quite High
Raphe 1 75.12 Quite High
Serotonin 3 72.92 Quite High
depression 17 69.56 Quite High
antidepressant 1 68.68 Quite High
Inflammatory response 1 60.20 Quite High
carbamazepine 9 53.92 Quite High
Neurotransmitter 2 19.64 Low Low
Disease Link Frequency Relevance Heat
Neurodegenerative Disease 14 95.04 Very High Very High Very High
INFLAMMATION 8 83.40 Quite High
Disease 77 78.08 Quite High
Diabetes Mellitus 4 77.80 Quite High
Stress 30 76.00 Quite High
Insulin Resistance 1 72.36 Quite High
Depression 20 69.56 Quite High
Apoptosis 23 67.84 Quite High
Shock 1 55.32 Quite High
Bladder Cancer 32 54.48 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
-catenin, as well as the transcription of Wnt target genes en-1 and cyclin-D1 [115].
Transcription (transcription) of catenin
1) Confidence 0.67 Published 2008 Journal Mol Neurodegener Section Body Doc Link PMC2515306 Disease Relevance 0.63 Pain Relevance 0.13
Five of the nine gene transcripts that were significantly altered in the kiwifruit group are annotated with known functions (Table 6) and are associated with signal transduction (G protein-coupled receptor 173 (GPR173) (down), creatine kinase muscle (CKM) (down), catenin-?
Transcription (transduction) of catenin in muscle
2) Confidence 0.67 Published 2010 Journal BMC Med Section Body Doc Link PMC2955589 Disease Relevance 0.20 Pain Relevance 0.03
-catenin transcription.
Transcription (transcription) of catenin
3) Confidence 0.67 Published 2010 Journal Human Genomics and Proteomics : HGP Section Body Doc Link PMC2958627 Disease Relevance 0.28 Pain Relevance 0.31
-catenin mRNA levels regardless of transfection status (Figure 5B-D) (p > .05 for all PCR comparisons, including target gene mRNA relative to ?
Transcription (levels) of catenin
4) Confidence 0.67 Published 2010 Journal J Exp Clin Cancer Res Section Body Doc Link PMC3020166 Disease Relevance 0.05 Pain Relevance 0

General Comments

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