INT242174

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.41
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 2.58
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (JUP) cell morphogenesis (JUP) structural molecule activity (JUP)
plasma membrane (JUP) cytoskeleton (JUP) nucleus (JUP)
JUP (Homo sapiens)
Pain Link Frequency Relevance Heat
Central nervous system 6 37.36 Quite Low
Hippocampus 3 32.48 Quite Low
nMDA receptor 1 7.04 Low Low
Kinase C 13 5.00 Very Low Very Low Very Low
agonist 9 5.00 Very Low Very Low Very Low
depression 6 5.00 Very Low Very Low Very Low
cINOD 4 5.00 Very Low Very Low Very Low
Inflammation 4 5.00 Very Low Very Low Very Low
Nicotine 3 5.00 Very Low Very Low Very Low
Opioid 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disease 61 99.84 Very High Very High Very High
Neuroblastoma 50 99.64 Very High Very High Very High
Cancer 45 99.08 Very High Very High Very High
Pheochromocytoma 33 98.36 Very High Very High Very High
Drug Induced Neurotoxicity 12 95.80 Very High Very High Very High
Glioma 2 81.12 Quite High
Medulloblastoma 1 69.00 Quite High
Brain Tumor 1 67.88 Quite High
Apoptosis 14 65.84 Quite High
Hepatocellular Cancer 1 65.72 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
-catenin levels are markedly reduced in AD patients carrying presenilin-1 (PS-1) inherited mutations [29].
Negative_regulation (reduced) of Gene_expression (levels) of catenin associated with disease
1) Confidence 0.41 Published 2008 Journal Mol Neurodegener Section Body Doc Link PMC2515306 Disease Relevance 0.85 Pain Relevance 0
Although Amitay et al. (2001) reported reduced expression of CTNNG in 9/20 neuroblastoma tumours, we observed promoter methylation in only 11% of neuroblastoma tumours and did not detect promoter methylation in the cell lines that demonstrated an increase expression of CTNNG after 5-aza-dC treatment.
Negative_regulation (reduced) of Gene_expression (expression) of CTNNG associated with neuroblastoma and cancer
2) Confidence 0.37 Published 2008 Journal Endocrine-Related Cancer Section Body Doc Link PMC2519165 Disease Relevance 1.73 Pain Relevance 0

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox