INT242178

Context Info Confidence 0.01 First Reported 2008 Last Reported 2008 Negated 0 Speculated 0 Reported most in Abstract Documents 1 Total Number 1 Disease Relevance 0.35 Pain Relevance 0

cytosol (CYP19A1) mitochondrion (Cyp11a1) small molecule metabolic process (CYP19A1) endoplasmic reticulum (CYP19A1) cytoplasm (CYP19A1)

CYP19A1 (Homo sapiens) Cyp11a1 (Rattus norvegicus)

Pain Link Frequency Relevance Heat withdrawal 1 5.00 Pain 1 5.00 antagonist 1 5.00

Disease Link Frequency Relevance Heat Death 29 99.48 Breast Cancer 29 98.36 Apoptosis 33 25.00 Cancer 3 5.00 Endometriosis (extended) 3 5.00 Disease 2 5.00 Hypersensitivity 2 5.00 Pain 1 5.00 Thrombosis Related Under Development 1 5.00 Osteoporotic Fractures 1 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Aromatase, the cytochrome P-450 enzyme (CYP19) responsible for estrogen biosynthesis, is an important target for the treatment of estrogen-dependent breast cancer.

Aromatase Regulation (target) of cytochrome P-450 enzyme associated with breast cancer

1) Confidence 0.01 Published 2008 Journal BMC Cell Biol Section Abstract Doc Link PMC2515307 Disease Relevance 0.35 Pain Relevance 0

General Comments

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