INT242196

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Context Info
Confidence 0.09
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 1.71
Pain Relevance 0.15

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (F3) aging (F3) extracellular region (F3)
plasma membrane (F3) cytoplasm (F3)
Anatomy Link Frequency
macrophages 3
smooth muscle cells 1
F3 (Homo sapiens)
Pain Link Frequency Relevance Heat
adenocard 2 92.08 High High
cINOD 2 57.84 Quite High
cva 50 50.00 Quite Low
ischemia 20 35.56 Quite Low
Bioavailability 5 32.56 Quite Low
aspirin 18 5.00 Very Low Very Low Very Low
antagonist 5 5.00 Very Low Very Low Very Low
Inflammation 4 5.00 Very Low Very Low Very Low
abdominal pain 2 5.00 Very Low Very Low Very Low
backache 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Injury 2 96.32 Very High Very High Very High
Hemorrhage 93 95.88 Very High Very High Very High
Adhesions 2 94.96 High High
Coagulation Disorder 8 92.80 High High
Rupture 12 78.28 Quite High
Stress 2 73.72 Quite High
Atherosclerotic Plaque 2 63.08 Quite High
Acute Coronary Syndrome 54 55.56 Quite High
Thrombosis 29 55.44 Quite High
Thrombosis Related Under Development 2 52.28 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
A dose-dependent prolongation of PT, activated partial thromboplastin time (aPTT), and HepTest to a similar extent to inhibition of FXa were seen, and it was suggested that the inhibition of the FXa activity of rivaroxaban can be monitored by these clotting tests or by measurement of FXa alone (Kubitza 2005a).
Positive_regulation (activated) of Localization (prolongation) of thromboplastin associated with coagulation disorder
1) Confidence 0.09 Published 2008 Journal Vascular Health and Risk Management Section Body Doc Link PMC2597756 Disease Relevance 0.44 Pain Relevance 0.06
In addition, activated macrophages and smooth muscle cells from the exposed necrotic core release tissue factor (TF) leading to activation of the coagulation cascade (Arora and Dhir 2005) and thrombin production (Sciulli and Mauro 2002).
Positive_regulation (leading) of Localization (release) of tissue factor in macrophages
2) Confidence 0.02 Published 2008 Journal Vascular Health and Risk Management Section Body Doc Link PMC2515410 Disease Relevance 0.63 Pain Relevance 0.05
In addition, activated macrophages and smooth muscle cells from the exposed necrotic core release tissue factor (TF) leading to activation of the coagulation cascade (Arora and Dhir 2005) and thrombin production (Sciulli and Mauro 2002).
Positive_regulation (leading) of in smooth muscle cells Localization (release) of tissue factor in macrophages
3) Confidence 0.01 Published 2008 Journal Vascular Health and Risk Management Section Body Doc Link PMC2515410 Disease Relevance 0.63 Pain Relevance 0.05

General Comments

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