INT242204

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Context Info
Confidence 0.03
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.66
Pain Relevance 0.10

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (DPP4, GLP1R) small molecule metabolic process (GLP1R) Golgi apparatus (DPP4)
endoplasmic reticulum (DPP4) signal transducer activity (GLP1R) peptidase activity (DPP4)
Anatomy Link Frequency
plasma 2
DPP4 (Homo sapiens)
GLP1R (Homo sapiens)
Pain Link Frequency Relevance Heat
agonist 2 99.90 Very High Very High Very High
Inflammation 4 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
Inflammatory response 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Diabetes Mellitus 104 99.26 Very High Very High Very High
Hypoglycemia 17 83.60 Quite High
Hyperglycemia 12 81.36 Quite High
Cardiovascular Disease 50 80.04 Quite High
Weight Gain 16 42.08 Quite Low
Myocardial Infarction 24 34.16 Quite Low
Obesity 12 5.00 Very Low Very Low Very Low
Disease 12 5.00 Very Low Very Low Very Low
Pressure And Volume Under Development 8 5.00 Very Low Very Low Very Low
Stroke 8 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
GLP-1 secretion may be impaired in T2DM, and GLP-1 analogs and agonists and DPP-4 inhibitors that increase endogenous GLP-1 production have the advantage that their effect on insulin secretion depends on plasma glucose concentration.
DPP-4 Positive_regulation (increase) of Gene_expression (production) of GLP-1 in plasma associated with diabetes mellitus and agonist
1) Confidence 0.03 Published 2008 Journal Vascular Health and Risk Management Section Body Doc Link PMC2515417 Disease Relevance 0.66 Pain Relevance 0.10

General Comments

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