INT242208

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Context Info
Confidence 0.29
First Reported 2008
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 7
Total Number 7
Disease Relevance 3.15
Pain Relevance 0.52

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (SRGN) extracellular region (SRGN) Golgi apparatus (SRGN)
SRGN (Homo sapiens)
Pain Link Frequency Relevance Heat
agonist 47 94.72 High High
antagonist 40 91.52 High High
Dopamine 25 90.92 High High
Serotonin 5 90.40 High High
imagery 5 88.88 High High
isoflurane 10 67.60 Quite High
Multiple sclerosis 1 42.32 Quite Low
Neuritis 1 35.92 Quite Low
Central nervous system 10 22.80 Low Low
depression 10 20.68 Low Low
Disease Link Frequency Relevance Heat
Glaucoma 51 100.00 Very High Very High Very High
Optic Disorders 16 99.40 Very High Very High Very High
Myopia 346 99.36 Very High Very High Very High
Disease 16 98.68 Very High Very High Very High
Hyperglycemia 12 92.40 High High
Diabetes Mellitus 104 88.08 High High
Ocular Hypertension 3 83.16 Quite High
Hypoglycemia 17 52.20 Quite High
Disease Progression 2 50.28 Quite High
Cardiovascular Disease 50 48.88 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Based on these five points, a revised diagnostic approach of glaucoma at the preperimetric stage is considered such that the subjective clinical diagnosis of GON as the reference standard in diagnosing PPG would probably be changed by adopting the available and more accurate alternative: objective and quantitative assessment of the peripapillary RNFL thickness loss.
Regulation (changed) of Gene_expression (diagnosing) of PPG associated with glaucoma and optic disorders
1) Confidence 0.29 Published 2010 Journal The Open Ophthalmology Journal Section Body Doc Link PMC2928913 Disease Relevance 1.10 Pain Relevance 0.04
When OADs no longer adequately control PPG excursions, prandial insulin can be added at mealtimes, one meal at a time, to a simple basal insulin regimen.
Regulation (control) of Gene_expression (excursions) of PPG
2) Confidence 0.19 Published 2008 Journal Vascular Health and Risk Management Section Body Doc Link PMC2515417 Disease Relevance 0.38 Pain Relevance 0
For statistical analyses and graphical representation of changes in ZENK and PPG RNA transcript expression, the mean normalized expression (MNE) of the target genes was calculated separately for each condition (treated, contralateral control, and age-matched untreated control retinal tissue).
Regulation (changes) of Gene_expression (expression) of PPG RNA transcript
3) Confidence 0.17 Published 2010 Journal Molecular Vision Section Body Doc Link PMC2855734 Disease Relevance 0.07 Pain Relevance 0.03
In this paper, we show that the molecular changes in expression of ZENK and PPG are similar in FDM and LIM, and that both FDM and LIM appear to produce similar changes in retinal circuitry that increase the sensitivity of retinal circuits to dopaminergic agonists and muscarinic cholinergic antagonists within 1 h of the commencement of visual manipulation.
Regulation (changes) of Gene_expression (expression) of PPG associated with antagonist, myopia and agonist
4) Confidence 0.17 Published 2010 Journal Molecular Vision Section Body Doc Link PMC2855734 Disease Relevance 0.56 Pain Relevance 0.40
The pattern of changes observed is consistent with a pathway in which down-regulation of ZENK expression is followed by the down-regulation of the expression of PPG transcripts.
Regulation (regulation) of Gene_expression (expression) of PPG
5) Confidence 0.13 Published 2010 Journal Molecular Vision Section Body Doc Link PMC2855734 Disease Relevance 0.50 Pain Relevance 0.04
However, after one day of diffuser wear, PPG expression was significantly down-regulated (t-test, p<0.05), and remained so for the duration of the form-deprivation period (t-test; 3 days p<0.05, 7 days p<0.01, and 10 days p<0.05).
Regulation (regulated) of Gene_expression (expression) of PPG
6) Confidence 0.13 Published 2010 Journal Molecular Vision Section Body Doc Link PMC2855734 Disease Relevance 0.28 Pain Relevance 0
Changes in PPG RNA transcript expression during the development of FDM and LIM
Regulation (Changes) of Gene_expression (expression) of PPG RNA transcript associated with myopia
7) Confidence 0.08 Published 2010 Journal Molecular Vision Section Body Doc Link PMC2855734 Disease Relevance 0.26 Pain Relevance 0

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