INT242259

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Context Info
Confidence 0.48
First Reported 2008
Last Reported 2010
Negated 1
Speculated 0
Reported most in Body
Documents 4
Total Number 4
Disease Relevance 1.44
Pain Relevance 0.59

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (CEBPZ) DNA binding (CEBPZ)
Anatomy Link Frequency
coronary artery 2
spinal cord 2
CEBPZ (Homo sapiens)
Pain Link Frequency Relevance Heat
Spinal cord 2 99.10 Very High Very High Very High
spinal-cord stimulation 17 98.32 Very High Very High Very High
Hippocampus 15 89.68 High High
medulla 8 87.76 High High
COX-2 inhibitor 1 80.16 Quite High
imagery 40 75.12 Quite High
positron emission tomography 18 64.52 Quite High
Somatosensory cortex 1 55.64 Quite High
tolerance 1 50.64 Quite High
amygdala 49 37.56 Quite Low
Disease Link Frequency Relevance Heat
Dyspnea 30 100.00 Very High Very High Very High
Atherosclerosis 2 97.96 Very High Very High Very High
Panic Disorder 36 97.28 Very High Very High Very High
Disease 9 86.52 High High
Vascular Dementia 1 85.56 High High
Aging 1 84.72 Quite High
Cerebrovascular Disease 2 80.40 Quite High
Cardiovascular Disease 2 78.40 Quite High
Brain Tumor 3 74.32 Quite High
Anxiety Disorder 108 61.24 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
This was not the case in patients who had panicked, but maybe because of induced hyperventilation decreasing CBF.
Neg (not) Negative_regulation (decreasing) of Neg (not) Positive_regulation (induced) of CBF associated with dyspnea
1) Confidence 0.48 Published 2008 Journal J Neural Transm Section Body Doc Link PMC2694920 Disease Relevance 0.73 Pain Relevance 0.15
Furthermore, our study is unique because we showed for the first time that a relationship exists between the estrogen-induced reduction in coronary sinus ET-1 levels and the degree of both the constriction of the coronary artery and the increase in CBF at the peak of AP in postmenopausal women without atherosclerotic coronary arteries.
Negative_regulation (reduction) of Positive_regulation (increase) of CBF in coronary artery associated with atherosclerosis
2) Confidence 0.33 Published 2008 Journal Vascular Health and Risk Management Section Body Doc Link PMC2515431 Disease Relevance 0.16 Pain Relevance 0
While the CBF response to functional activation was reduced by approximately 70%, the deoxy-Hb response was abolished (Figure 5) or even reversed into an increase of deoxy-Hb [see Supplementary Figure 3 in Leithner et al. (2010)] instead of the normal outwash response (Leithner et al., 2010).
Negative_regulation (reduced) of Positive_regulation (activation) of CBF
3) Confidence 0.31 Published 2010 Journal Frontiers in Neuroenergetics Section Body Doc Link PMC2955428 Disease Relevance 0.39 Pain Relevance 0.07
In experiments on rats, he showed that surgical sympathectomy failed to influence the CBF response caused by cervical SCS, while transsection of the spinal cord at the cervicomedullary junction completely abolished all increases in CBF.
Negative_regulation (abolished) of Positive_regulation (increases) of CBF in spinal cord associated with spinal cord and spinal-cord stimulation
4) Confidence 0.31 Published 2010 Journal Acta Neurochir (Wien) Section Body Doc Link PMC2901492 Disease Relevance 0.16 Pain Relevance 0.37

General Comments

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