INT242342

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Context Info
Confidence 0.09
First Reported 2008
Last Reported 2008
Negated 0
Speculated 1
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 2.03
Pain Relevance 0.15

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

pigmentation (Ednrb) aging (Ednrb) plasma membrane (Ednrb)
signal transducer activity (Ednrb)
Anatomy Link Frequency
fibroblasts 2
Ednrb (Rattus norvegicus)
Pain Link Frequency Relevance Heat
fibrosis 8 94.96 High High
antagonist 36 44.48 Quite Low
Bile 8 5.00 Very Low Very Low Very Low
Inflammation 4 5.00 Very Low Very Low Very Low
depression 2 5.00 Very Low Very Low Very Low
metalloproteinase 2 5.00 Very Low Very Low Very Low
cva 2 5.00 Very Low Very Low Very Low
headache 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Pulmonary Hypertension 142 98.80 Very High Very High Very High
Increased Venous Pressure Under Development 24 98.64 Very High Very High Very High
Fibrosis 10 94.96 High High
Disease 38 88.24 High High
Apoptosis 2 67.80 Quite High
Hypertrophy 6 58.92 Quite High
Heart Rate Under Development 8 6.40 Low Low
Pressure And Volume Under Development 16 5.80 Low Low
Systemic Sclerosis 12 5.00 Very Low Very Low Very Low
Hypoxia 8 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Because of the effects of a sub-population of ETB receptors located on SMC and fibroblasts, the spectrum of possible adverse effects of ETB-receptor stimulation in patients with pulmonary hypertension includes the induction of vasoconstriction,15,25 proliferation,24,26 and fibrosis.27
Regulation (population) of ETB in fibroblasts associated with fibrosis, pulmonary hypertension and increased venous pressure under development
1) Confidence 0.09 Published 2008 Journal European Heart Journal Section Body Doc Link PMC2515885 Disease Relevance 1.02 Pain Relevance 0.08
Because of the effects of a sub-population of ETB receptors located on SMC and fibroblasts, the spectrum of possible adverse effects of ETB-receptor stimulation in patients with pulmonary hypertension includes the induction of vasoconstriction,15,25 proliferation,24,26 and fibrosis.27
Spec (possible) Regulation (effects) of ETB-receptor in fibroblasts associated with fibrosis, pulmonary hypertension and increased venous pressure under development
2) Confidence 0.09 Published 2008 Journal European Heart Journal Section Body Doc Link PMC2515885 Disease Relevance 1.01 Pain Relevance 0.08

General Comments

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