INT242390

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Context Info
Confidence 0.31
First Reported 2008
Last Reported 2010
Negated 2
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 1.37
Pain Relevance 1.06

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

endosome (Bdkrb2) signal transduction (Bdkrb2) plasma membrane (Bdkrb2)
signal transducer activity (Bdkrb2)
Bdkrb2 (Mus musculus)
Pain Link Frequency Relevance Heat
Nicotine 96 100.00 Very High Very High Very High
b2 receptor 47 100.00 Very High Very High Very High
bradykinin 63 98.48 Very High Very High Very High
ischemia 16 89.28 High High
antagonist 19 88.80 High High
Central nervous system 19 82.20 Quite High
cytokine 17 76.24 Quite High
Inflammation 71 67.76 Quite High
B1 receptor 11 66.96 Quite High
chemokine 23 50.00 Quite Low
Disease Link Frequency Relevance Heat
Multiple Sclerosis 86 98.08 Very High Very High Very High
Disease 17 98.04 Very High Very High Very High
Cv Unclassified Under Development 12 89.28 High High
Reperfusion Injury 32 88.12 High High
INFLAMMATION 80 67.76 Quite High
Recurrence 1 53.52 Quite High
Brain Injury 1 31.28 Quite Low
Rhinitis 1 11.32 Low Low
Adhesions 15 10.16 Low Low
Inflammatory Pain 1 10.08 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Absence of B2 receptor did not modulate TNF-?
Neg (not) Regulation (modulate) of Neg (Absence) Gene_expression (Absence) of B2 receptor associated with b2 receptor
1) Confidence 0.31 Published 2008 Journal J Neuroinflammation Section Body Doc Link PMC2596102 Disease Relevance 1.02 Pain Relevance 0.35
In B1KO mice, B2R expression was not modified (data not shown).
Neg (not) Regulation (modified) of Gene_expression (expression) of B2R
2) Confidence 0.19 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2516176 Disease Relevance 0.34 Pain Relevance 0.26
Effects of nicotine on airway kinin B1 and B2 receptor mRNA and protein expressions
Regulation (Effects) of Gene_expression (expressions) of B2 receptor mRNA associated with nicotine and b2 receptor
3) Confidence 0.01 Published 2010 Journal Respir Res Section Body Doc Link PMC2845563 Disease Relevance 0 Pain Relevance 0.45

General Comments

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