INT242392

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Context Info
Confidence 0.18
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 3
Disease Relevance 1.65
Pain Relevance 0.76

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Scr (Mus musculus)
Pain Link Frequency Relevance Heat
antagonist 21 99.60 Very High Very High Very High
ischemia 39 93.08 High High
bradykinin 30 85.52 High High
agonist 15 79.36 Quite High
Inflammation 72 69.32 Quite High
cytokine 18 59.44 Quite High
Inflammatory response 12 5.00 Very Low Very Low Very Low
chemokine 6 5.00 Very Low Very Low Very Low
ketamine 3 5.00 Very Low Very Low Very Low
anesthesia 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Reperfusion Injury 96 97.84 Very High Very High Very High
Cv Unclassified Under Development 36 93.08 High High
INFLAMMATION 87 69.32 Quite High
Injury 6 67.72 Quite High
Apoptosis 18 64.56 Quite High
Death 18 62.08 Quite High
Targeted Disruption 30 44.28 Quite Low
Renal Disease 6 25.68 Quite Low
Pressure And Volume Under Development 6 5.00 Very Low Very Low Very Low
Aggression 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Moreover, B1R antagonism (R-954) significantly reduced sCr levels at 24 hours (0.93±0.40 in treated versus 2.22±0.14 mg/dL in untreated animals, p?
Negative_regulation (reduced) of Gene_expression (levels) of sCr
1) Confidence 0.18 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2516176 Disease Relevance 0.69 Pain Relevance 0.25
B1KO had a significant reduction in sCr at all times analyzed, meanwhile B2KO mice presented lower sCr values only at 4 and 24 h.
Negative_regulation (presented) of Gene_expression (values) of sCr
2) Confidence 0.16 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2516176 Disease Relevance 0.35 Pain Relevance 0.26
Moreover, we found that B1R antagonist R-954 also able to reduce sCr levels.
Negative_regulation (reduce) of Gene_expression (levels) of sCr associated with antagonist
3) Confidence 0.16 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2516176 Disease Relevance 0.61 Pain Relevance 0.26

General Comments

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