INT242447

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Context Info
Confidence 0.35
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.16
Pain Relevance 0.06

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

endosome (Prf1) extracellular region (Prf1) structural molecule activity (Gfap)
cytoplasmic membrane-bounded vesicle (Prf1) plasma membrane (Prf1) extracellular matrix organization (Gfap)
Prf1 (Mus musculus)
Gfap (Mus musculus)
Pain Link Frequency Relevance Heat
Central nervous system 55 63.28 Quite High
imagery 12 5.00 Very Low Very Low Very Low
Inflammation 4 5.00 Very Low Very Low Very Low
cytokine 2 5.00 Very Low Very Low Very Low
Multiple sclerosis 2 5.00 Very Low Very Low Very Low
IPN 1 5.00 Very Low Very Low Very Low
cva 1 5.00 Very Low Very Low Very Low
medulla 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Multiple Sclerosis 21 82.16 Quite High
Infection 12 81.76 Quite High
Apoptosis 10 5.00 Very Low Very Low Very Low
Syndrome 6 5.00 Very Low Very Low Very Low
Cerebral Malaria 5 5.00 Very Low Very Low Very Low
Dengue Hemorrhagic Fever 5 5.00 Very Low Very Low Very Low
Viral Hemorrhagic Fevers 4 5.00 Very Low Very Low Very Low
INFLAMMATION 4 5.00 Very Low Very Low Very Low
Sprains And Strains 4 5.00 Very Low Very Low Very Low
Disease 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We determined from these experiments that perforin is necessary for upregulation of GFAP following VP2121–130 peptide administration.


perforin Positive_regulation (necessary) of Positive_regulation (upregulation) of GFAP
1) Confidence 0.35 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2516328 Disease Relevance 0.16 Pain Relevance 0.06

General Comments

This test has worked.

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