INT242463

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Context Info
Confidence 0.02
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 3
Disease Relevance 0.86
Pain Relevance 0.27

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

exf (Mus musculus)
Pain Link Frequency Relevance Heat
antagonist 12 100.00 Very High Very High Very High
vagus nerve 24 78.56 Quite High
agonist 70 75.60 Quite High
adenocard 1 67.84 Quite High
Intracerebroventricular 16 5.00 Very Low Very Low Very Low
Central nervous system 8 5.00 Very Low Very Low Very Low
Neuropeptide 4 5.00 Very Low Very Low Very Low
isoflurane 4 5.00 Very Low Very Low Very Low
anesthesia 2 5.00 Very Low Very Low Very Low
palliative 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cancer 57 100.00 Very High Very High Very High
Targeted Disruption 23 99.52 Very High Very High Very High
Infection 24 88.44 High High
Toxicity 1 29.32 Quite Low
Apoptosis 37 25.12 Quite Low
Hepatocellular Cancer 78 19.24 Low Low
Hyperglycemia 24 5.00 Very Low Very Low Very Low
Hyperinsulinism 10 5.00 Very Low Very Low Very Low
Pressure And Volume Under Development 8 5.00 Very Low Very Low Very Low
Death 7 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Colony formation assay and ex vivo tumor inhibition
Negative_regulation (inhibition) of ex vivo associated with cancer
1) Confidence 0.02 Published 2008 Journal Carcinogenesis Section Body Doc Link PMC2516489 Disease Relevance 0.48 Pain Relevance 0.03
The metabolic and vascular effects of Ex4 were markedly attenuated by central infusion of the GLP-1 receptor (GLP-1R) antagonist exendin-9 (Ex9) and totally abolished in GLP-1 receptor knockout mice.
Negative_regulation (abolished) of Ex4 associated with targeted disruption and antagonist
2) Confidence 0.02 Published 2008 Journal Diabetes Section Abstract Doc Link PMC2551665 Disease Relevance 0.18 Pain Relevance 0.12
A correlation was observed between the metabolic rate and the vascular flow in control and Ex4-infused mice, which disappeared in Ex9 and GLP-1R knockout mice.
Negative_regulation (disappeared) of Ex9 associated with targeted disruption
3) Confidence 0.02 Published 2008 Journal Diabetes Section Abstract Doc Link PMC2551665 Disease Relevance 0.19 Pain Relevance 0.12

General Comments

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