INT242479

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Context Info
Confidence 0.14
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.28
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (Ciapin1, Bcl2) nucleus (Ciapin1, Bcl2) mitochondrion (Bcl2)
cell morphogenesis (Bcl2) endoplasmic reticulum (Bcl2) intracellular (Bcl2)
Ciapin1 (Mus musculus)
Bcl2 (Mus musculus)
Pain Link Frequency Relevance Heat
Potency 1 47.96 Quite Low
palliative 1 5.00 Very Low Very Low Very Low
cytokine 1 5.00 Very Low Very Low Very Low
adenocard 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Hepatocellular Cancer 78 99.12 Very High Very High Very High
Apoptosis 37 98.84 Very High Very High Very High
Cancer 57 97.72 Very High Very High Very High
Targeted Disruption 7 10.72 Low Low
Death 7 8.16 Low Low
Infection 24 5.00 Very Low Very Low Very Low
Hepatitis 6 5.00 Very Low Very Low Very Low
Hematological Disease 4 5.00 Very Low Very Low Very Low
Cirrhosis 4 5.00 Very Low Very Low Very Low
Adenovirus Infection 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We found that depletion of CIAPIN1 could downregulate Bcl-2 and Bcl-XL and upregulate Bax in AdSiCIAPIN1-transduced tumor cells, suggesting that Bcl-2 family members may contribute partially to the apoptosis of HCC cells with CIAPIN1 depletion.
Negative_regulation (depletion) of CIAPIN1 Negative_regulation (downregulate) of Bcl-2 associated with cancer, hepatocellular cancer and apoptosis
1) Confidence 0.14 Published 2008 Journal Carcinogenesis Section Body Doc Link PMC2516489 Disease Relevance 1.28 Pain Relevance 0

General Comments

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