INT242566

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Context Info
Confidence 0.02
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.23
Pain Relevance 0.32

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (Krt14) structural molecule activity (Krt14) nucleus (Krt14)
intracellular (Krt14) cytoplasm (Krt14)
Anatomy Link Frequency
skin 2
Krt14 (Mus musculus)
Pain Link Frequency Relevance Heat
c fibre 17 99.96 Very High Very High Very High
TRP channel 7 84.40 Quite High
unmyelinated 4 70.96 Quite High
Calcitonin gene-related peptide 22 55.04 Quite High
Lasting pain 1 54.96 Quite High
withdrawal 1 52.08 Quite High
Spinal cord 4 44.28 Quite Low
nociceptor 19 14.56 Low Low
Nerve growth factor 29 5.00 Very Low Very Low Very Low
substance P 8 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Targeted Disruption 14 100.00 Very High Very High Very High
Pain 1 54.96 Quite High
Ganglion Cysts 66 50.00 Quite Low
Apoptosis 8 5.00 Very Low Very Low Very Low
Death 7 5.00 Very Low Very Low Very Low
Sprains And Strains 6 5.00 Very Low Very Low Very Low
Ocular Toxicity (including Many Sub-types) 6 5.00 Very Low Very Low Very Low
INFLAMMATION 2 5.00 Very Low Very Low Very Low
Hyperalgesia 1 5.00 Very Low Very Low Very Low
Nociception 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Overexpression of GDNF in transgenic mice under control of the K14 keratin gene promoter results in a six-fold increase of GDNF protein in skin (Zwick et al. 2002).
Positive_regulation (Overexpression) of Regulation (control) of K14 keratin gene promoter in skin associated with targeted disruption
1) Confidence 0.02 Published 2008 Journal Cell Tissue Res Section Body Doc Link PMC2516536 Disease Relevance 0.23 Pain Relevance 0.32

General Comments

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