INT242575

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Context Info
Confidence 0.18
First Reported 2008
Last Reported 2008
Negated 1
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.15
Pain Relevance 0.64

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transport (Accn2) plasma membrane (Accn2)
Accn2 (Mus musculus)
Pain Link Frequency Relevance Heat
c fibre 17 91.92 High High
action potential duration 1 88.76 High High
Calcitonin gene-related peptide 22 63.60 Quite High
nociceptor 19 56.08 Quite High
TRP channel 7 54.16 Quite High
Spinal cord 4 47.08 Quite Low
unmyelinated 4 20.84 Low Low
hyperexcitability 1 10.00 Low Low
Nerve growth factor 29 5.00 Very Low Very Low Very Low
substance P 8 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Targeted Disruption 14 81.20 Quite High
Ganglion Cysts 66 50.00 Quite Low
Apoptosis 8 5.00 Very Low Very Low Very Low
Death 7 5.00 Very Low Very Low Very Low
Sprains And Strains 6 5.00 Very Low Very Low Very Low
Ocular Toxicity (including Many Sub-types) 6 5.00 Very Low Very Low Very Low
INFLAMMATION 2 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
Hyperalgesia 1 5.00 Very Low Very Low Very Low
Nociception 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Analysis of the expression of putative mechanosensitive ion channels by RT-PCR shows increased mRNA levels for acid-sensitive ion channel 2a (ASIC2a) and ASIC2b but not for ASIC1 and ASIC3 in GDNF-overexpressing animals.
Neg (not) Positive_regulation (increased) of Transcription (levels) of ASIC2a
1) Confidence 0.18 Published 2008 Journal Cell Tissue Res Section Body Doc Link PMC2516536 Disease Relevance 0.15 Pain Relevance 0.64

General Comments

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