INT242605

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Context Info
Confidence 0.26
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0.17
Pain Relevance 1.30

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transport (Trpv1) transmembrane transport (Trpv1) lipid metabolic process (Trpv1)
cell proliferation (Gdnf) cytosol (Trpv1) extracellular space (Gdnf)
Anatomy Link Frequency
nociceptor 1
Gdnf (Mus musculus)
Trpv1 (Mus musculus)
Pain Link Frequency Relevance Heat
substance P 16 100.00 Very High Very High Very High
nociceptor 38 99.44 Very High Very High Very High
Neuropeptide 14 98.04 Very High Very High Very High
Nerve growth factor 58 97.76 Very High Very High Very High
Inflammation 4 93.12 High High
qutenza 10 91.04 High High
Freund adjuvant 2 90.48 High High
imagery 2 76.08 Quite High
tetrodotoxin 6 63.84 Quite High
sodium channel 6 55.40 Quite High
Disease Link Frequency Relevance Heat
INFLAMMATION 4 93.12 High High
Ganglion Cysts 132 50.00 Quite Low
Targeted Disruption 28 18.88 Low Low
Apoptosis 16 5.00 Very Low Very Low Very Low
Death 14 5.00 Very Low Very Low Very Low
Sprains And Strains 12 5.00 Very Low Very Low Very Low
Ocular Toxicity (including Many Sub-types) 12 5.00 Very Low Very Low Very Low
Pain 2 5.00 Very Low Very Low Very Low
Hyperalgesia 2 5.00 Very Low Very Low Very Low
Nociception 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The GDNF-induced increase in TRPV1 IR in long-term culture is similar to that affected by NGF (Bron et al. 2003).
GDNF Positive_regulation (increase) of TRPV1 associated with nerve growth factor
1) Confidence 0.26 Published 2008 Journal Cell Tissue Res Section Body Doc Link PMC2516536 Disease Relevance 0.09 Pain Relevance 0.76
In vitro, GDNF increases the proportion of neurons positive for SP and TRPV1, markers for nociceptor subpopulations.
GDNF Positive_regulation (increases) of TRPV1 in nociceptor associated with nociceptor and substance p
2) Confidence 0.24 Published 2008 Journal Cell Tissue Res Section Body Doc Link PMC2516536 Disease Relevance 0.08 Pain Relevance 0.54

General Comments

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