INT242607

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Context Info
Confidence 0.16
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0.39

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

kinase activity (Ntrk1, Ret) cell differentiation (Ntrk1) signal transduction (Ret)
plasma membrane (Ntrk1) cytoplasm (Ntrk1)
Anatomy Link Frequency
nociceptors 2
Ntrk1 (Mus musculus)
Ret (Mus musculus)
Pain Link Frequency Relevance Heat
nociceptor 19 100.00 Very High Very High Very High
Nerve growth factor 29 98.44 Very High Very High Very High
cytokine 1 84.44 Quite High
Calcitonin gene-related peptide 22 5.00 Very Low Very Low Very Low
c fibre 17 5.00 Very Low Very Low Very Low
substance P 8 5.00 Very Low Very Low Very Low
Neuropeptide 7 5.00 Very Low Very Low Very Low
TRP channel 7 5.00 Very Low Very Low Very Low
qutenza 5 5.00 Very Low Very Low Very Low
noradrenaline 5 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Ganglion Cysts 66 50.00 Quite Low
Targeted Disruption 14 5.00 Very Low Very Low Very Low
Apoptosis 8 5.00 Very Low Very Low Very Low
Death 7 5.00 Very Low Very Low Very Low
Sprains And Strains 6 5.00 Very Low Very Low Very Low
Ocular Toxicity (including Many Sub-types) 6 5.00 Very Low Very Low Very Low
INFLAMMATION 2 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
Hyperalgesia 1 5.00 Very Low Very Low Very Low
Nociception 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The postnatal downregulation of trkA in these cells to form ret-positive trkA-negative non-peptidergic nociceptors in turn requires ret.
Negative_regulation (downregulation) of trkA in nociceptors Positive_regulation (requires) of ret associated with nociceptor
1) Confidence 0.16 Published 2008 Journal Cell Tissue Res Section Body Doc Link PMC2516536 Disease Relevance 0 Pain Relevance 0.39

General Comments

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