INT242753

Context Info Confidence 0.09 First Reported 2008 Last Reported 2008 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0.16 Pain Relevance 0.51

peptidase activity (Naalad2) cellular_component (Naalad2)

Naalad2 (Mus musculus)

Pain Term Frequency Confidence Heat Glutamate receptor 5 100.00 Neuropeptide 1 95.00 gABA 3 93.52 Glutamate 3 93.16 Pain 19 80.88 analgesia 17 78.92 Eae 14 77.16 agonist 8 54.40 Intracerebroventricular 15 50.00 Analgesic 12 50.00

Disease Term Frequency Confidence Heat Pain 19 80.88 Inflammatory Pain 12 77.16 INFLAMMATION 5 42.88 Neuropathic Pain 4 41.76 Bone Cancer 2 40.08 Nociception 3 16.64 Overdose 1 5.00 Toxicity 1 5.00 Akathisia 1 5.00 Abnormal Reflex 1 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Synaptically released NAAG activates the group II metabotropic glutamate receptors [mGluR3 >> mGluR2; [6-8]].

NAAG Positive_regulation (activates) of glutamate receptors associated with glutamate receptor

1) Confidence 0.09 Published 2008 Journal Mol Pain Section Body Doc Link PMC2517065 Disease Relevance 0.16 Pain Relevance 0.51

General Comments

This test has worked.