INT24279

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.75
First Reported 1987
Last Reported 2010
Negated 0
Speculated 1
Reported most in Abstract
Documents 11
Total Number 12
Disease Relevance 12.46
Pain Relevance 2.80

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (INSL3) extracellular region (INSL3) cell-cell signaling (INSL3)
Anatomy Link Frequency
pancreas 2
acinar cells 2
INSL3 (Homo sapiens)
Pain Link Frequency Relevance Heat
Chronic pancreatitis 37 99.84 Very High Very High Very High
endometriosis 4 99.60 Very High Very High Very High
Dismenorea 4 94.88 High High
Pain 54 92.44 High High
Chronic low back pain 6 5.00 Very Low Very Low Very Low
backache 5 5.00 Very Low Very Low Very Low
Lasting pain 3 5.00 Very Low Very Low Very Low
imagery 2 5.00 Very Low Very Low Very Low
cINOD 1 5.00 Very Low Very Low Very Low
depression 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cancer 49 99.92 Very High Very High Very High
Pancreatitis 37 99.84 Very High Very High Very High
Pancreatic Cancer 76 99.78 Very High Very High Very High
Endometriosis 11 99.60 Very High Very High Very High
Hyperplasia 9 98.16 Very High Very High Very High
Malignant Neoplastic Disease 20 95.80 Very High Very High Very High
Pain 28 92.44 High High
Apoptosis 6 90.32 High High
Anxiety Disorder 19 89.04 High High
Lymphatic System Cancer 1 78.76 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The values for F, E, RLF, LLF, RLR and LLR were expressed in degrees.


Gene_expression (expressed) of RLF
1) Confidence 0.75 Published 2010 Journal International Journal of Yoga Section Body Doc Link PMC2952120 Disease Relevance 0.33 Pain Relevance 0.09
Fas and Ley were expressed randomly across a wide range in both the eutopic and ectopic endometrial tissues.
Gene_expression (expressed) of Ley
2) Confidence 0.13 Published 1996 Journal Mol. Hum. Reprod. Section Abstract Doc Link 9238697 Disease Relevance 1.43 Pain Relevance 0.50
Unlike Lex antigens, Ley-related antigens were expressed in 32-77% of specimens of normal pancreas, with similar frequencies in specimens of chronic pancreatitis and pancreatic cancer.
Gene_expression (expressed) of Ley in pancreas associated with pancreatic cancer and chronic pancreatitis
3) Confidence 0.13 Published 1988 Journal Cancer Res. Section Abstract Doc Link 3335015 Disease Relevance 1.12 Pain Relevance 0.26
Lex and Ley antigen expression in human pancreatic cancer.
Gene_expression (expression) of Ley associated with pancreatic cancer
4) Confidence 0.13 Published 1988 Journal Cancer Res. Section Title Doc Link 3335015 Disease Relevance 0.58 Pain Relevance 0.12
The discrepant expression between Lex and Ley antigens in these tissues implies altered regulation of fucosyltransferase activity associated with the malignant state.
Gene_expression (expression) of Ley associated with malignant neoplastic disease
5) Confidence 0.13 Published 1988 Journal Cancer Res. Section Abstract Doc Link 3335015 Disease Relevance 1.01 Pain Relevance 0.16
The present comparative immunohistochemical study used tissues of normal pancreas, chronic pancreatitis, and pancreatic cancer to determine the normal expression of Lex and Ley antigens in the pancreas and to elucidate any cancer-associated alterations.
Spec (determine) Gene_expression (expression) of Ley in pancreas associated with cancer, pancreatic cancer and chronic pancreatitis
6) Confidence 0.13 Published 1988 Journal Cancer Res. Section Abstract Doc Link 3335015 Disease Relevance 0.83 Pain Relevance 0.19
Also in cancer specimens, simple Lex and simple Lex antigens were often concordantly expressed, whereas extended Lex and extended Ley antigen expression was often discordant.
Gene_expression (expression) of Ley associated with cancer
7) Confidence 0.13 Published 1988 Journal Cancer Res. Section Abstract Doc Link 3335015 Disease Relevance 1.28 Pain Relevance 0.28
In pancreatic cancer, extended Ley antigen expression was found in less than 10% of poorly differentiated tumors.
Gene_expression (expression) of Ley associated with cancer and pancreatic cancer
8) Confidence 0.13 Published 1988 Journal Cancer Res. Section Abstract Doc Link 3335015 Disease Relevance 1.30 Pain Relevance 0.29
In normal pancreas, simple Ley was expressed by both ductal and acinar cells, but extended Ley antigens were expressed only by acinar cells.
Gene_expression (expressed) of Ley in acinar cells
9) Confidence 0.13 Published 1988 Journal Cancer Res. Section Abstract Doc Link 3335015 Disease Relevance 1.24 Pain Relevance 0.29
Coexpression among the Ley-related antigens was less common than with the Lex-related antigens.
Gene_expression (Coexpression) of Ley
10) Confidence 0.13 Published 1988 Journal Cancer Res. Section Abstract Doc Link 3335015 Disease Relevance 1.31 Pain Relevance 0.29
In normal pancreas, simple Ley was expressed by both ductal and acinar cells, but extended Ley antigens were expressed only by acinar cells.
Gene_expression (expressed) of Ley in acinar cells
11) Confidence 0.09 Published 1988 Journal Cancer Res. Section Abstract Doc Link 3335015 Disease Relevance 1.18 Pain Relevance 0.25
Antigens T, Lex, Sialo-Lex and Ley were also expressed in chronic pancreatitis but the chance of monoclonal antibodies staining in these tissues (18 approximately 36%) was markedly lower than the staining in cancer tissues (54 approximately 77%) except Ley.
Gene_expression (expressed) of Ley associated with cancer and chronic pancreatitis
12) Confidence 0.04 Published 1987 Journal Zhonghua Zhong Liu Za Zhi Section Abstract Doc Link 2452061 Disease Relevance 0.84 Pain Relevance 0.10

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox