INT242823

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.36
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 3
Disease Relevance 6.00
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (CTNND2) cell adhesion (CTNND2) nucleus (CTNND2)
cytoplasm (CTNND2)
Anatomy Link Frequency
Thyroid 2
CTNND2 (Homo sapiens)
Pain Link Frequency Relevance Heat
imagery 24 5.00 Very Low Very Low Very Low
Central nervous system 18 5.00 Very Low Very Low Very Low
Pain 6 5.00 Very Low Very Low Very Low
Inflammation 3 5.00 Very Low Very Low Very Low
ischemia 3 5.00 Very Low Very Low Very Low
abdominal pain 3 5.00 Very Low Very Low Very Low
alcohol 3 5.00 Very Low Very Low Very Low
headache 3 5.00 Very Low Very Low Very Low
cva 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Familial Adenomatous Polyposis 327 100.00 Very High Very High Very High
Apoptosis 3 96.44 Very High Very High Very High
Chromosomal Instability 3 93.44 High High
Intestinal Cancer 6 92.04 High High
Thyroid Neoplasm 39 88.40 High High
Disease 33 85.24 High High
Hypertrophy 6 71.48 Quite High
Adenoma 30 70.28 Quite High
Brain Tumor 51 69.24 Quite High
Pancreatic Cancer 27 68.68 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
-catenin accumulates in the cytoplasm and binds to several transcription factors of the TCF/LEF, thereby altering the expression of various genes affecting proliferation, differentiation, migration and apoptosis of cells.13 In addition, APC stabilizes microtubules, leading to chromosomal stability.15,16 Inactivation of APC can lead to defective chromosome segregation and aberrant mitosis.17

FAP and Thyroid Carcinoma

catenin Binding (binds) of in Thyroid associated with thyroid neoplasm, chromosomal instability, familial adenomatous polyposis and apoptosis
1) Confidence 0.36 Published 2008 Journal Ann Surg Oncol Section Body Doc Link PMC2518080 Disease Relevance 1.99 Pain Relevance 0
-catenin accumulates in the cytoplasm and binds to several transcription factors of the TCF/LEF, thereby altering the expression of various genes affecting proliferation, differentiation, migration and apoptosis of cells.13 In addition, APC stabilizes microtubules, leading to chromosomal stability.15,16 Inactivation of APC can lead to defective chromosome segregation and aberrant mitosis.17

FAP and Thyroid Carcinoma

catenin Binding (altering) of in Thyroid associated with thyroid neoplasm, chromosomal instability, familial adenomatous polyposis and apoptosis
2) Confidence 0.36 Published 2008 Journal Ann Surg Oncol Section Body Doc Link PMC2518080 Disease Relevance 2.09 Pain Relevance 0
-catenin activity.14 In the absence of a Wnt signal, APC forms a complex with the protein ?
catenin Binding (complex) of associated with familial adenomatous polyposis
3) Confidence 0.36 Published 2008 Journal Ann Surg Oncol Section Body Doc Link PMC2518080 Disease Relevance 1.92 Pain Relevance 0

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox