INT242847

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Context Info
Confidence 0.17
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 3
Disease Relevance 0.56
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell proliferation (TGFBI) extracellular space (TGFBI) extracellular region (TGFBI)
plasma membrane (TGFBI) extracellular matrix organization (TGFBI)
CDB2 (Homo sapiens)
TGFBI (Homo sapiens)
Pain Link Frequency Relevance Heat
Pain 6 34.28 Quite Low
Disease Link Frequency Relevance Heat
Recurrence 21 98.80 Very High Very High Very High
Cicatrix 3 88.04 High High
Amyloid Plaque 9 83.64 Quite High
Disease 24 77.48 Quite High
Amyloidosis 6 75.12 Quite High
Alzheimer's Dementia 6 62.72 Quite High
Low Vision 3 43.20 Quite Low
Adhesions 12 31.36 Quite Low
Keloid Scars 12 14.64 Low Low
Calcification 6 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
This novel genotype-phenotype correlation challenges our current knowledge of the “phenotypic specificity” that CDB1 segregates with the R124L genotype, and CDB2 with R555Q.
CDB2 Binding (segregates) of CDB1
1) Confidence 0.17 Published 2008 Journal Molecular Vision Section Body Doc Link PMC2518171 Disease Relevance 0 Pain Relevance 0
The recurrence of the dystrophy after corneal transplantation is noted to be early with CDB1 and much later with CDB2 [5].
CDB2 Binding (be) of CDB1 associated with recurrence
2) Confidence 0.13 Published 2008 Journal Molecular Vision Section Body Doc Link PMC2518171 Disease Relevance 0.10 Pain Relevance 0
This genotype-phenotype correlation is unique from two perspectives: First -historically CDB has predominantly been associated with 2 different distinct mutations; R124L with CDB1, and R555Q with CDB2 [13].
CDB2 Binding (associated) of CDB
3) Confidence 0.10 Published 2008 Journal Molecular Vision Section Body Doc Link PMC2518171 Disease Relevance 0.46 Pain Relevance 0

General Comments

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