INT242878

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Context Info
Confidence 0.04
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.81
Pain Relevance 0.27

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (INS) small molecule metabolic process (INS) extracellular region (INS)
RNA binding (SPI1) nucleus (SPI1) carbohydrate metabolic process (INS)
INS (Homo sapiens)
SPI1 (Homo sapiens)
Pain Link Frequency Relevance Heat
ischemia 3 92.44 High High
Inflammation 18 91.52 High High
metalloproteinase 1 57.44 Quite High
cytokine 1 56.24 Quite High
Inflammatory response 3 5.00 Very Low Very Low Very Low
Inflammatory mediators 1 5.00 Very Low Very Low Very Low
cINOD 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Injury 3 99.12 Very High Very High Very High
Cv Unclassified Under Development 3 92.44 High High
INFLAMMATION 23 91.52 High High
Endotoxemia 2 88.80 High High
Syndrome 1 87.76 High High
Atherosclerosis 8 87.36 High High
Infection 2 87.28 High High
Acute Coronary Syndrome 1 86.00 High High
Reperfusion Injury 1 82.84 Quite High
Obesity 6 71.20 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In conclusion, insulin suppresses TLR expression and the activity of the transcription factor PU.1.
insulin Negative_regulation (suppresses) of Gene_expression (expression) of PU.1
1) Confidence 0.04 Published 2008 Journal Diabetes Care Section Body Doc Link PMC2518353 Disease Relevance 1.81 Pain Relevance 0.27

General Comments

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