INT242898

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Context Info
Confidence 0.33
First Reported 2008
Last Reported 2008
Negated 1
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.88
Pain Relevance 0.11

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (MYD88) signal transduction (MYD88) plasma membrane (MYD88)
intracellular (MYD88) cytoplasm (MYD88)
MYD88 (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 24 88.40 High High
Inflammatory response 16 59.88 Quite High
ischemia 3 5.00 Very Low Very Low Very Low
Restless leg syndrome 1 5.00 Very Low Very Low Very Low
cytokine 1 5.00 Very Low Very Low Very Low
cINOD 1 5.00 Very Low Very Low Very Low
alcohol 1 5.00 Very Low Very Low Very Low
Inflammatory mediators 1 5.00 Very Low Very Low Very Low
metalloproteinase 1 5.00 Very Low Very Low Very Low
tolerance 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Atherosclerosis 47 93.68 High High
INFLAMMATION 42 88.40 High High
Disease 17 75.16 Quite High
Peripheral Arterial Disease 54 67.68 Quite High
Diabetes Mellitus 17 56.72 Quite High
Adhesions 1 6.44 Low Low
Insulin Resistance 10 5.00 Very Low Very Low Very Low
Disease Progression 7 5.00 Very Low Very Low Very Low
Obesity 6 5.00 Very Low Very Low Very Low
Hypertension 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Data shown in this setting demonstrate that genes involved in TLR-mediated pathway are significantly up-regulated in intermediate or advanced lesions, including TLR1, TLR2, TLR7, and MyD88.
Regulation (regulated) of MyD88
1) Confidence 0.33 Published 2008 Journal BMC Genomics Section Body Doc Link PMC2529314 Disease Relevance 0.82 Pain Relevance 0.11
MyD88 and CD14 expression was not significantly altered following insulin infusion (data not shown).


Neg (not) Regulation (altered) of MyD88
2) Confidence 0.12 Published 2008 Journal Diabetes Care Section Body Doc Link PMC2518353 Disease Relevance 0.06 Pain Relevance 0

General Comments

This test has worked.

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