INT242900

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.26
First Reported 2008
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 1.12
Pain Relevance 0.23

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

RNA binding (SPI1) nucleus (SPI1)
Anatomy Link Frequency
MNCs 1
SPI1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 68 98.16 Very High Very High Very High
COX2 3 96.52 Very High Very High Very High
Inflammatory response 12 63.64 Quite High
ischemia 6 5.00 Very Low Very Low Very Low
cytokine 5 5.00 Very Low Very Low Very Low
cINOD 2 5.00 Very Low Very Low Very Low
Inflammatory mediators 2 5.00 Very Low Very Low Very Low
metalloproteinase 2 5.00 Very Low Very Low Very Low
fibrosis 1 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 84 98.16 Very High Very High Very High
Esophageal Disease 36 88.84 High High
Stomach Cancer 1 81.72 Quite High
Diabetes Mellitus 34 77.28 Quite High
Obesity 12 67.60 Quite High
Toxicity 20 50.00 Quite Low
Non-small-cell Lung Cancer 8 41.72 Quite Low
Pneumonia 36 40.16 Quite Low
Insulin Resistance 20 5.00 Very Low Very Low Very Low
Atherosclerosis 16 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
However, this same variant, while altering the Sp1/Sp3 site, also introduces a binding site for another transcription factor, Egr-1, although the consequences are unknown [22].
Regulation (altering) of Sp1
1) Confidence 0.26 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2928273 Disease Relevance 0.66 Pain Relevance 0.17
Effect of insulin infusion on PU.1
Regulation (Effect) of PU.1
2) Confidence 0.08 Published 2008 Journal Diabetes Care Section Body Doc Link PMC2518353 Disease Relevance 0.05 Pain Relevance 0
The DNA binding of PU.1, a major transcription factor regulating many TLR genes, was concomitantly suppressed by 24 ± 10% (P < 0.05) by 4 h in MNCs.
Regulation (regulating) of PU.1 in MNCs
3) Confidence 0.08 Published 2008 Journal Diabetes Care Section Abstract Doc Link PMC2518353 Disease Relevance 0.41 Pain Relevance 0.06

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox