INT242910

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Context Info
Confidence 0.05
First Reported 2008
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 2.24
Pain Relevance 0.06

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

molecular_function (Bcl2a1c) cellular_component (Bcl2a1c) biological_process (Bcl2a1c)
Bcl2a1c (Mus musculus)
Pain Link Frequency Relevance Heat
Pain 7 56.96 Quite High
aspirin 28 5.00 Very Low Very Low Very Low
tolerance 16 5.00 Very Low Very Low Very Low
peripheral neuropathy 7 5.00 Very Low Very Low Very Low
fibrosis 6 5.00 Very Low Very Low Very Low
diabetic neuropathy 4 5.00 Very Low Very Low Very Low
Calcium channel 4 5.00 Very Low Very Low Very Low
depression 4 5.00 Very Low Very Low Very Low
alcohol 3 5.00 Very Low Very Low Very Low
corticosteroid 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Neuropathic Pain 76 99.98 Very High Very High Very High
Hyperglycemia 47 99.96 Very High Very High Very High
Diabetes Mellitus 567 90.88 High High
Disorder Of Lipid Metabolism 17 77.64 Quite High
Hypertension 43 75.92 Quite High
Hyperhomocysteinemia 3 72.16 Quite High
Cardiovascular Disease 92 71.36 Quite High
Disease 13 66.44 Quite High
Hypoglycemia 68 65.08 Quite High
Frailty 6 62.08 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The odds of neuropathy increase for each percent increase in A1C; the risk for neuropathy is twice as great for someone with an A1C of 9 versus 6%.
Positive_regulation (increase) of Positive_regulation (increase) of A1C associated with neuropathic pain
1) Confidence 0.05 Published 2008 Journal Diabetes Care Section Body Doc Link PMC2518355 Disease Relevance 1.34 Pain Relevance 0.06
It is clear that postprandial hyperglycemia, like preprandial hyperglycemia, contributes to elevated A1C levels, with its relative contribution being higher at A1C levels that are closer to 7%.
Positive_regulation (contributes) of Positive_regulation (elevated) of A1C associated with hyperglycemia
2) Confidence 0.01 Published 2010 Journal Diabetes Care Section Body Doc Link PMC2797382 Disease Relevance 0.90 Pain Relevance 0

General Comments

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