INT242947

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Context Info
Confidence 0.02
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.11
Pain Relevance 0.08

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (PDE1B) signal transduction (PDE1B) nucleolus (PDE1B)
nucleus (PDE1B) cytoplasm (PDE1B)
PDE1B (Homo sapiens)
Pain Link Frequency Relevance Heat
Neurotransmitter 7 61.64 Quite High
Central nervous system 13 52.88 Quite High
long-term potentiation 17 5.00 Very Low Very Low Very Low
Hippocampus 9 5.00 Very Low Very Low Very Low
Multiple sclerosis 7 5.00 Very Low Very Low Very Low
Inflammation 4 5.00 Very Low Very Low Very Low
Pain 3 5.00 Very Low Very Low Very Low
nMDA receptor 2 5.00 Very Low Very Low Very Low
Angina 2 5.00 Very Low Very Low Very Low
headache 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Reprotox - General 2 10 55.76 Quite High
Pressure And Volume Under Development 7 52.48 Quite High
Neurological Disease 4 34.32 Quite Low
Neurodegenerative Disease 20 5.00 Very Low Very Low Very Low
Disease 20 5.00 Very Low Very Low Very Low
Demyelinating Disease 7 5.00 Very Low Very Low Very Low
Cognitive Disorder 6 5.00 Very Low Very Low Very Low
Stress 4 5.00 Very Low Very Low Very Low
INFLAMMATION 4 5.00 Very Low Very Low Very Low
Stroke 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
For example many effects of Ca2+ on cAMP and cGMP are mediated by the activation of the Ca2+-Calmodulin (Ca2+-CaM) dependent phosphorylation of PDEs (Sonnenburg et al 1995).
Phosphorylation (phosphorylation) of PDEs
1) Confidence 0.02 Published 2008 Journal Neuropsychiatric Disease and Treatment Section Body Doc Link PMC2518390 Disease Relevance 0.11 Pain Relevance 0.08

General Comments

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