INT242971

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.04
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 1.62
Pain Relevance 0.07

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mRNA processing (Ern1) endoplasmic reticulum (Ern1) kinase activity (Ern1)
response to stress (Ern1)
Anatomy Link Frequency
leaflet 1
Ern1 (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 8 76.08 Quite High
cytokine 4 63.32 Quite High
chemokine 2 5.00 Very Low Very Low Very Low
tolerance 2 5.00 Very Low Very Low Very Low
anesthesia 2 5.00 Very Low Very Low Very Low
Kinase C 2 5.00 Very Low Very Low Very Low
Inflammatory response 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Stress 62 99.82 Very High Very High Very High
Cancer 12 99.04 Very High Very High Very High
Necrosis 6 98.80 Very High Very High Very High
Obesity 94 85.28 High High
Insulin Resistance 18 77.92 Quite High
INFLAMMATION 10 76.08 Quite High
Ovarian Cancer 2 44.48 Quite Low
Metastasis 2 34.96 Quite Low
Breast Cancer 2 30.48 Quite Low
Shock 2 15.40 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
JNK activation is coupled to ER stress–induced IRE-1 activation through recruitment of tumor necrosis factor receptor–associated factor-2 and apotosis signal–regulating kinase-1 to the cytosolic leaflet of the ER membrane (22).
Positive_regulation (activation) of IRE-1 in leaflet associated with stress, necrosis and cancer
1) Confidence 0.04 Published 2008 Journal Diabetes Section Body Doc Link PMC2518495 Disease Relevance 0.75 Pain Relevance 0.04
IRE-1 activation results in dimerization and autophosphorylation of IRE-1.
Positive_regulation (activation) of IRE-1
2) Confidence 0.04 Published 2008 Journal Diabetes Section Body Doc Link PMC2518495 Disease Relevance 0.87 Pain Relevance 0.03

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox