INT242991

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Context Info
Confidence 0.21
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.66
Pain Relevance 0.26

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Agt, Spp1) extracellular region (Spp1) cell adhesion (Spp1)
extracellular matrix organization (Agt) cytoplasm (Spp1)
Anatomy Link Frequency
cardiomyocyte 2
Agt (Mus musculus)
Spp1 (Mus musculus)
Pain Link Frequency Relevance Heat
fibrosis 73 97.92 Very High Very High Very High
Inflammation 17 93.08 High High
agonist 2 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
Inflammatory response 1 5.00 Very Low Very Low Very Low
imagery 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Fibrosis 18 97.92 Very High Very High Very High
INFLAMMATION 17 93.08 High High
Targeted Disruption 10 81.12 Quite High
Cardiovascular Disorder Under Development 56 68.24 Quite High
Injury 2 57.96 Quite High
Coronary Heart Disease 28 23.76 Low Low
Body Weight 7 18.56 Low Low
Myocardial Infarction 6 5.00 Very Low Very Low Very Low
Stress 4 5.00 Very Low Very Low Very Low
Diabetes Mellitus 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Because AngII markedly enhanced cardiomyocyte OPN expression, cardiomyocyte-mediated macrophage chemotaxis (Fig. 4B and C), and in vivo macrophage recruitment (32), we hypothesized that pioglitazone could attenuate fibrosis via anti-inflammatory actions on macrophages.
AngII Positive_regulation (enhanced) of Gene_expression (expression) of OPN in cardiomyocyte associated with fibrosis and inflammation
1) Confidence 0.21 Published 2008 Journal Diabetes Section Body Doc Link PMC2518499 Disease Relevance 0.66 Pain Relevance 0.26

General Comments

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