INT243198

Context Info Confidence 0.09 First Reported 2008 Last Reported 2010 Negated 0 Speculated 0 Reported most in Body Documents 2 Total Number 5 Disease Relevance 4.05 Pain Relevance 0.09

endosome (ZNRF1) ligase activity (ZNRF1) lysosome (ZNRF1)

ZNRF1 (Homo sapiens)

Pain Link Frequency Relevance Heat emotional pain 17 87.96 Pain 11 5.00 depression 2 5.00 Paracetamol 1 5.00

Disease Link Frequency Relevance Heat Injury 431 100.00 Personality Disorder 2 100.00 Affective Disorder 1 100.00 Psychosis 3 95.24 Death 5 94.76 Brain Injury 1 88.60 Keloid Scars 12 88.48 Pain 32 87.96 Intellectual Impairment 1 87.96 Infection 5 84.52

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

It appears that prohibition of self-injury does not, in and of itself, assist the individual to develop the capacity to choose reasonably and with confidence.

Gene_expression (prohibition) of self-injury associated with injury

1) Confidence 0.09 Published 2010 Journal Theor Med Bioeth Section Body Doc Link PMC2847158 Disease Relevance 0.41 Pain Relevance 0

In each scenario, do the practitioners help self-injury to occur or persist?

Gene_expression (help) of self-injury associated with injury

2) Confidence 0.09 Published 2010 Journal Theor Med Bioeth Section Body Doc Link PMC2847158 Disease Relevance 0.24 Pain Relevance 0

The care team is aware of the early warning signs of the self-injury escalating beyond an agreed level and has the patient’s permission to intervene if this occurs.7

Gene_expression (aware) of self-injury associated with injury

3) Confidence 0.09 Published 2010 Journal Theor Med Bioeth Section Body Doc Link PMC2847158 Disease Relevance 0.81 Pain Relevance 0

Or, is the approach more likely to minimise harm, by ensuring safer self-injury?

Gene_expression (safer) of self-injury associated with injury

4) Confidence 0.09 Published 2010 Journal Theor Med Bioeth Section Abstract Doc Link PMC2847158 Disease Relevance 0.57 Pain Relevance 0.09

Only repetitive self-injury, usually seen in people with mood disorders and personality disorders [14,15,26,27], is addressed in these guidelines, and the typical patterns and motivations are described below.

Gene_expression (addressed) of self-injury associated with affective disorder, personality disorder and injury

5) Confidence 0.08 Published 2008 Journal BMC Psychiatry Section Body Doc Link PMC2518920 Disease Relevance 2.01 Pain Relevance 0

General Comments

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