INT243216

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Context Info
Confidence 0.00
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.75
Pain Relevance 0.11

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (Myst2) intracellular (Myst2) transferase activity, transferring acyl groups (Myst2)
cytoplasm (VEGFA) extracellular space (VEGFA) extracellular region (VEGFA)
Anatomy Link Frequency
neuronal 2
Myst2 (Mus musculus)
VEGFA (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 6 91.12 High High
cytokine 12 65.04 Quite High
ischemia 4 5.00 Very Low Very Low Very Low
cva 3 5.00 Very Low Very Low Very Low
Migraine 2 5.00 Very Low Very Low Very Low
imagery 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Neurodegenerative Disease 1 100.00 Very High Very High Very High
Cerebral Malaria 62 99.90 Very High Very High Very High
INFLAMMATION 6 91.12 High High
Brain Injury 2 84.40 Quite High
Hypothermia 5 74.60 Quite High
Death 7 50.00 Quite Low
Malaria 1 30.76 Quite Low
Coma 4 12.72 Low Low
Hyperoxia 4 8.20 Low Low
Parasitemia 21 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Therefore, we cannot rule out that other mechanisms are also involved in HBO neuroprotective effects in ECM, as HBO also inhibits ICAM-1 expression and neuronal apoptosis and upregulates the expression of vascular endothelial growth factor (VEGF), which is involved in angiogenesis in human endothelial cells [22], [23], [25], [28], [59].
HBO Positive_regulation (upregulates) of Gene_expression (expression) of VEGF in neuronal associated with neurodegenerative disease and cerebral malaria
1) Confidence 0.00 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2518956 Disease Relevance 0.75 Pain Relevance 0.11

General Comments

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