INT243249

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Context Info
Confidence 0.18
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 8
Disease Relevance 3.85
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

structural molecule activity (Nefl) locomotion (Nefl)
Anatomy Link Frequency
retina 3
optic nerve head 2
ganglion cell 1
optic nerve 1
Nefl (Mus musculus)
Pain Link Frequency Relevance Heat
gABA 40 5.00 Very Low Very Low Very Low
GABAergic 40 5.00 Very Low Very Low Very Low
Glutamate 16 5.00 Very Low Very Low Very Low
Spinal cord 8 5.00 Very Low Very Low Very Low
anesthesia 8 5.00 Very Low Very Low Very Low
Neurotransmitter 8 5.00 Very Low Very Low Very Low
Somatostatin 8 5.00 Very Low Very Low Very Low
imagery 8 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Ganglion Cysts 512 99.84 Very High Very High Very High
Neurodegenerative Disease 8 88.32 High High
Targeted Disruption 152 50.00 Quite Low
Ocular Toxicity (including Many Sub-types) 8 5.00 Very Low Very Low Very Low
Sprains And Strains 8 5.00 Very Low Very Low Very Low
Increased Venous Pressure Under Development 8 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Finally, colocalization of CFP expression and NF-L immunoreactivity was evident in ganglion cell axons in the nerve fiber layer, optic nerve head, and optic nerve (Figure 4J-L).
Regulation (immunoreactivity) of NF-L in optic nerve head associated with ganglion cysts
1) Confidence 0.18 Published 2008 Journal Molecular Vision Section Body Doc Link PMC2519030 Disease Relevance 0.46 Pain Relevance 0
In addition, NF-L immunoreactivity was localized to dendrites in all laminae of the IPL and to individual axons that formed thick bundles in the fiber layer that became increasingly frequent in central retina (Figure 4B,E).
Regulation (immunoreactivity) of NF-L in retina
2) Confidence 0.18 Published 2008 Journal Molecular Vision Section Body Doc Link PMC2519030 Disease Relevance 0.55 Pain Relevance 0
In transverse sections of the thy1-CFP mouse retina, NF-L immunoreactivity was characterized by prominent immunostaining that was restricted primarily to the inner retina; weak NF-L immunoreactivity was observed in ganglion cell bodies, and immunostaining was characterized by a reticular appearance.
Regulation (immunoreactivity) of NF-L in retina associated with ganglion cysts
3) Confidence 0.18 Published 2008 Journal Molecular Vision Section Body Doc Link PMC2519030 Disease Relevance 0.57 Pain Relevance 0
Colocalization of CFP and NF-L immunoreactivities was determined from confocal images of the GCL from five retinal wholemounts (Table 1).
Regulation (immunoreactivities) of NF-L
4) Confidence 0.18 Published 2008 Journal Molecular Vision Section Body Doc Link PMC2519030 Disease Relevance 0.40 Pain Relevance 0
In transverse sections of the thy1-CFP mouse retina, NF-L immunoreactivity was characterized by prominent immunostaining that was restricted primarily to the inner retina; weak NF-L immunoreactivity was observed in ganglion cell bodies, and immunostaining was characterized by a reticular appearance.
Regulation (immunoreactivity) of NF-L in retina associated with ganglion cysts
5) Confidence 0.18 Published 2008 Journal Molecular Vision Section Body Doc Link PMC2519030 Disease Relevance 0.56 Pain Relevance 0
CFP expression colocalized with NF-L immunoreactivity in ganglion cell bodies in the GCL (Figure 4C,F) and dendrites in the IPL.
Regulation (immunoreactivity) of NF-L in ganglion cell associated with ganglion cysts
6) Confidence 0.18 Published 2008 Journal Molecular Vision Section Body Doc Link PMC2519030 Disease Relevance 0.44 Pain Relevance 0
In wholemounts, NF-L immunoreactivity in the GCL was found in numerous somata that varied in size from small to very large, and in the optic fiber layer immunolabeled fiber bundles (Figure 4H) converged in a radial pattern at the optic nerve head (Figure 4L).
Regulation (immunoreactivity) of NF-L in optic nerve head
7) Confidence 0.18 Published 2008 Journal Molecular Vision Section Body Doc Link PMC2519030 Disease Relevance 0.40 Pain Relevance 0
Finally, colocalization of CFP expression and NF-L immunoreactivity was evident in ganglion cell axons in the nerve fiber layer, optic nerve head, and optic nerve (Figure 4J-L).
Regulation (immunoreactivity) of NF-L in optic nerve associated with ganglion cysts
8) Confidence 0.06 Published 2008 Journal Molecular Vision Section Body Doc Link PMC2519030 Disease Relevance 0.46 Pain Relevance 0

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