INT243325

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Context Info
Confidence 0.45
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 4
Disease Relevance 1.38
Pain Relevance 1.03

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (TPT1) extracellular space (TPT1) transcription factor binding (TPT1)
cytoplasm (TPT1)
TPT1 (Homo sapiens)
Pain Link Frequency Relevance Heat
cytokine 8 100.00 Very High Very High Very High
Somatosensory cortex 104 99.84 Very High Very High Very High
primary somatosensory cortex 4 95.20 Very High Very High Very High
Thalamus 46 89.84 High High
medulla 6 87.92 High High
Substantia nigra 10 81.64 Quite High
Inflammation 12 56.80 Quite High
imagery 32 5.00 Very Low Very Low Very Low
isoflurane 4 5.00 Very Low Very Low Very Low
cerebral cortex 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Death 40 100.00 Very High Very High Very High
Apoptosis 22 100.00 Very High Very High Very High
Absence Epilepsy 24 85.36 High High
Convulsion 32 60.84 Quite High
INFLAMMATION 12 56.80 Quite High
Necrosis 4 38.84 Quite Low
Cancer 4 38.48 Quite Low
Hyperplasia 10 11.48 Low Low
Epilepsy 30 5.00 Very Low Very Low Very Low
Increased Venous Pressure Under Development 12 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The genes TPT1 (or histamine releasing factor), cytokine induced apoptosis inhibitor 1 (cIAP-1), mitochondrial PUMA (BBC3), cathepsin B (CTSB), ATP6V0A1, cathepsin L and LAMP2, all of which are associated with cell-death related responses, were differentially expressed after the 1 h exposure to L. plantarum WCFS1.
Gene_expression (expressed) of TPT1 associated with apoptosis, death and cytokine
1) Confidence 0.45 Published 2008 Journal BMC Genomics Section Body Doc Link PMC2519092 Disease Relevance 0.62 Pain Relevance 0.14
The genes TPT1 (or histamine releasing factor), cytokine induced apoptosis inhibitor 1 (cIAP-1), mitochondrial PUMA (BBC3), cathepsin B (CTSB), ATP6V0A1, cathepsin L and LAMP2, all of which are associated with cell-death related responses, were differentially expressed after the 1 h exposure to L. plantarum WCFS1.
Gene_expression (expressed) of histamine releasing factor associated with apoptosis, death and cytokine
2) Confidence 0.45 Published 2008 Journal BMC Genomics Section Body Doc Link PMC2519092 Disease Relevance 0.62 Pain Relevance 0.14
The HRF in S1BF (in blue) was much slower (half-width = 21 s, ?
Gene_expression (The) of HRF associated with somatosensory cortex
3) Confidence 0.06 Published 2008 Journal PLoS Biology Section Body Doc Link PMC2605917 Disease Relevance 0 Pain Relevance 0.35
The HRF was found to last significantly longer in S1BF than in other ROIs (Figure 3A).
Gene_expression (found) of HRF associated with somatosensory cortex
4) Confidence 0.06 Published 2008 Journal PLoS Biology Section Body Doc Link PMC2605917 Disease Relevance 0.15 Pain Relevance 0.40

General Comments

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