INT243392

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Context Info
Confidence 0.64
First Reported 2008
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 2.36
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (CST6)
CST6 (Homo sapiens)
Pain Link Frequency Relevance Heat
Opioid 4 5.00 Very Low Very Low Very Low
metalloproteinase 3 5.00 Very Low Very Low Very Low
medulla 2 5.00 Very Low Very Low Very Low
Catecholamine 2 5.00 Very Low Very Low Very Low
Chronic pancreatitis 1 5.00 Very Low Very Low Very Low
tolerance 1 5.00 Very Low Very Low Very Low
Inflammation 1 5.00 Very Low Very Low Very Low
wide dynamic range 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Pancreatic Cancer 46 99.84 Very High Very High Very High
Cancer 114 95.96 Very High Very High Very High
Neuroblastoma 100 91.20 High High
Apoptosis 8 87.52 High High
Metastasis 3 84.40 Quite High
Malignant Neoplastic Disease 4 82.88 Quite High
Breast Cancer 4 77.20 Quite High
Pheochromocytoma 66 58.56 Quite High
Necrosis 1 42.64 Quite Low
Disease 9 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
However, there was no correlation between the extent CST6 CpG island methylation and upregulation of CST6 expression after 5-aza-dC treatment.
Positive_regulation (upregulation) of Gene_expression (expression) of CST6
1) Confidence 0.64 Published 2008 Journal Endocrine-Related Cancer Section Body Doc Link PMC2519165 Disease Relevance 0.53 Pain Relevance 0
However, there was no correlation between the extent CST6 CpG island methylation and upregulation of CST6 expression after 5-aza-dC treatment.
Positive_regulation (upregulation) of Gene_expression (expression) of CST6
2) Confidence 0.46 Published 2008 Journal Endocrine-Related Cancer Section Body Doc Link PMC2519165 Disease Relevance 0.53 Pain Relevance 0
While cystatin M expression in pancreatic cancer is not well studied, a recent study reports cystatin M is overexpressed in pancreatic tumors, and addition of functional cystatin M to culture media promotes cell proliferation.35
Positive_regulation (overexpressed) of Gene_expression (overexpressed) of cystatin M associated with pancreatic cancer
3) Confidence 0.21 Published 2009 Journal Journal of Proteome Research Section Body Doc Link PMC2652408 Disease Relevance 1.30 Pain Relevance 0

General Comments

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