INT243415

Context Info Confidence 0.10 First Reported 2008 Last Reported 2010 Negated 1 Speculated 0 Reported most in Body Documents 2 Total Number 2 Disease Relevance 1.73 Pain Relevance 0.15

cell adhesion (EMB)

Anatomy Link Frequency myocardium 1 heart 1 EMB (Homo sapiens)

Pain Link Frequency Relevance Heat Inflammation 67 97.76 addiction 1 20.60 imagery 13 5.36 cytokine 2 5.00 depression 2 5.00 Inflammatory response 2 5.00 isoflurane 2 5.00 cva 2 5.00 anesthesia 1 5.00 fibrosis 1 5.00

Disease Link Frequency Relevance Heat INFLAMMATION 59 97.76 Infection 8 97.04 Acute Myocarditis 132 82.64 Sarcoidosis 1 76.48 Cardiomyopathy 12 75.52 Cv General 4 Under Development 1 74.44 Myocardial Infarction 11 72.44 Heart Rate Under Development 9 67.36 Chronic Disease 1 67.28 Myocarditis 10 65.88

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Mutation

Event

Anatomy

Negation

Speculation

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Disease term

In another study Mahrholdt et al.[4] were able to increase sensitivity of EMB by taking biopsy close to contrast enhanced myocardium.

Positive_regulation (increase) of EMB in myocardium

1) Confidence 0.10 Published 2010 Journal J Cardiovasc Magn Reson Section Body Doc Link PMC2936396 Disease Relevance 0.52 Pain Relevance 0.10

However, these assays do not prove direct presence of virus infection in the heart due to the high background prevalence, and hence they can be helpful to identify the aetiology in a selected patient group who do not undergo EMB for additional PCR and immunohistochemical analysis of inflammation.

Neg (not) Positive_regulation (undergo) of EMB in heart associated with inflammation and infection

2) Confidence 0.07 Published 2008 Journal European Heart Journal Section Body Doc Link PMC2519249 Disease Relevance 1.20 Pain Relevance 0.05

General Comments

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