INT243467

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Context Info
Confidence 0.08
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.62
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

small molecule metabolic process (PCSK1, POMC) cell-cell signaling (PCSK1, POMC) extracellular space (PCSK1, POMC)
cellular nitrogen compound metabolic process (PCSK1, POMC) Golgi apparatus (PCSK1) embryo development (PCSK1)
PCSK1 (Homo sapiens)
POMC (Homo sapiens)
Pain Link Frequency Relevance Heat
agonist 2 5.00 Very Low Very Low Very Low
fibrosis 2 5.00 Very Low Very Low Very Low
Dopamine 2 5.00 Very Low Very Low Very Low
Somatostatin 2 5.00 Very Low Very Low Very Low
headache 1 5.00 Very Low Very Low Very Low
imagery 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cancer 76 98.68 Very High Very High Very High
Adenoma 79 93.00 High High
Rhinitis 2 83.28 Quite High
Acth-secreting Pituitary Adenoma 3 77.04 Quite High
Recurrence 2 75.72 Quite High
Graves' Ophthalmopathy 1 75.68 Quite High
Disease 3 75.04 Quite High
Basophil Adenoma 1 11.56 Low Low
Pituitary Cancer 35 5.00 Very Low Very Low Very Low
Carcinoma 7 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The tumor cells produce prohormone, proopiomelanocortin (POMC), from which ACTH is derived after proper proteolytic digestion by prohormone convertase (PC1/3).
prohormone convertase Positive_regulation (derived) of ACTH associated with cancer
1) Confidence 0.08 Published 2008 Journal Histochem Cell Biol Section Body Doc Link PMC2522328 Disease Relevance 1.62 Pain Relevance 0

General Comments

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