INT243481

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Context Info
Confidence 0.50
First Reported 2008
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 3.34
Pain Relevance 0.62

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (GATA2) nucleolus (GATA2) nucleus (GATA2)
protein complex (GATA2) transcription factor binding (GATA2)
Anatomy Link Frequency
Pit 1
GATA2 (Homo sapiens)
Pain Link Frequency Relevance Heat
Migraine 61 87.52 High High
fibrosis 2 78.24 Quite High
Inflammation 3 68.48 Quite High
cva 3 11.76 Low Low
aspirin 3 5.00 Very Low Very Low Very Low
headache 3 5.00 Very Low Very Low Very Low
Dopamine 2 5.00 Very Low Very Low Very Low
agonist 2 5.00 Very Low Very Low Very Low
Somatostatin 2 5.00 Very Low Very Low Very Low
5HT 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Coronary Artery Disease 67 98.98 Very High Very High Very High
Rheumatoid Arthritis 19 98.18 Very High Very High Very High
Adenoma 79 95.28 Very High Very High Very High
Cancer 78 94.96 High High
Headache 48 87.52 High High
Migraine Without Aura 7 83.64 Quite High
Migraine With Aura 18 80.84 Quite High
Fibrosis 2 78.24 Quite High
Neurodegenerative Disease 4 74.80 Quite High
Nephritis 1 72.80 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In correspondence with an RA-induced profile in CD34+ cells from CAD patients, these cells showed a concomitant higher expression of the transcription factor GATA2, which has been reported to functionally cooperate with RAR?
Gene_expression (expression) of GATA2 associated with coronary artery disease and rheumatoid arthritis
1) Confidence 0.50 Published 2010 Journal BMC Genomics Section Body Doc Link PMC2901320 Disease Relevance 1.47 Pain Relevance 0.03
Six family members of have been identified in vertebrates to be part of the GATA family and have been subdivided in two groups: GATA-1, GATA-2, and GATA-3, which are expressed in the hematopoetic system [19].
Gene_expression (expressed) of GATA-2
2) Confidence 0.43 Published 2008 Journal The Open Neurology Journal Section Body Doc Link PMC2577932 Disease Relevance 0.56 Pain Relevance 0.51
For transcription factors, Pit-1 (d) and GATA-2 (e) are positive and sometimes ER (f) is positive


Gene_expression (positive) of GATA-2 in Pit
3) Confidence 0.12 Published 2008 Journal Histochem Cell Biol Section Body Doc Link PMC2522328 Disease Relevance 1.31 Pain Relevance 0.07

General Comments

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