INT243494

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Context Info
Confidence 0.01
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0.06
Pain Relevance 1.06

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell proliferation (LOC308670) transmembrane transport (LOC308670) cytoplasm (Vta1)
Vta1 (Rattus norvegicus)
LOC308670 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Nicotine 108 100.00 Very High Very High Very High
Ventral tegmentum 68 100.00 Very High Very High Very High
midbrain 6 92.48 High High
amygdala 4 82.48 Quite High
Dopamine 34 79.36 Quite High
Substantia nigra 8 75.20 Quite High
deep brain stimulation 8 63.44 Quite High
gABA 8 53.52 Quite High
Glutamate 4 52.80 Quite High
projection neuron 2 18.80 Low Low
Disease Link Frequency Relevance Heat
Disease 2 60.40 Quite High
Parkinson's Disease 8 42.72 Quite Low
Depression 12 5.00 Very Low Very Low Very Low
Calcification 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The present data, taken together with the intravenous self-administration studies of Alderson and her colleagues (2006), strengthen the belief that the pPPTg has a role to play in mediating the behavioural effects of nicotine through interaction with the VTA.
VTA Binding (interaction) of pPPTg associated with ventral tegmentum and nicotine
1) Confidence 0.01 Published 2008 Journal Brain Struct Funct Section Body Doc Link PMC2522332 Disease Relevance 0 Pain Relevance 0.81
The data are consistent with the hypothesis that the pPPTg is more strongly associated with VTA function rather than SNC, unlike the aPPTg which has the reverse pattern.
VTA Binding (associated) of pPPTg associated with ventral tegmentum
2) Confidence 0.01 Published 2008 Journal Brain Struct Funct Section Body Doc Link PMC2522332 Disease Relevance 0.06 Pain Relevance 0.24

General Comments

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