INT243550

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Context Info
Confidence 0.25
First Reported 2008
Last Reported 2011
Negated 0
Speculated 0
Reported most in Body
Documents 7
Total Number 7
Disease Relevance 7.49
Pain Relevance 0.40

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (PSPH) small molecule metabolic process (PSPH) cellular nitrogen compound metabolic process (PSPH)
cytoplasm (PSPH)
Anatomy Link Frequency
PSP 5
section 3 1
PSPH (Homo sapiens)
Pain Link Frequency Relevance Heat
Action potential 7 96.48 Very High Very High Very High
sodium channel 51 92.88 High High
Paresthesia 4 84.88 Quite High
Pain 4 79.12 Quite High
Neurotransmitter 13 78.72 Quite High
potassium channel 3 62.08 Quite High
Calcium channel 21 5.00 Very Low Very Low Very Low
tetrodotoxin 21 5.00 Very Low Very Low Very Low
agonist 12 5.00 Very Low Very Low Very Low
antagonist 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Shellfish Poisoning 266 100.00 Very High Very High Very High
Poisoning 113 100.00 Very High Very High Very High
Toxicity 80 99.92 Very High Very High Very High
Death 25 96.68 Very High Very High Very High
Respiratory Paralysis 2 96.28 Very High Very High Very High
Williams-beuren Syndrome 1 92.56 High High
Sleep Disorders 5 92.12 High High
Ataxia 7 91.64 High High
Drug Induced Neurotoxicity 6 90.96 High High
Muscle Weakness 2 88.96 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Mammals, birds, and fish can be affected by PSP toxins; however, humans are the most sensitive—the fatal oral dose of saxitoxin is 1–4?
Gene_expression (toxins) of PSP in PSP associated with shellfish poisoning
1) Confidence 0.25 Published 2011 Journal International Journal of Microbiology Section Body Doc Link PMC2957129 Disease Relevance 1.20 Pain Relevance 0.17
Females had a lower expression of genes encoding phosphoserine phosphatase, an enzyme that catalyzes L-serine formation.
Gene_expression (expression) of phosphoserine phosphatase
2) Confidence 0.16 Published 2009 Journal Molecular Vision Section Body Doc Link PMC2790476 Disease Relevance 0.82 Pain Relevance 0.08
Since then, members of three dinoflagellate genera have been reported to be the major sources of PSP toxins: Alexandrium, Gymnodinium, and Pyrodinium [23].
Gene_expression (sources) of PSP in PSP associated with shellfish poisoning
3) Confidence 0.11 Published 2008 Journal Marine Drugs Section Body Doc Link PMC2525493 Disease Relevance 0.68 Pain Relevance 0
This review summarizes the origin, structure and clinical symptoms of PSP, NSP, CFP, AZP, yessotoxin and palytoxin produced by marine dinoflagellates, as well as their molecular mechanisms of action on voltage-gated ion channels.


1.

Gene_expression (produced) of PSP in PSP associated with shellfish poisoning and poisoning
4) Confidence 0.11 Published 2008 Journal Marine Drugs Section Abstract Doc Link PMC2525493 Disease Relevance 1.48 Pain Relevance 0
This paper provides a brief overview of the origin, structure and clinical symptoms of PSP, NSP, CFP, AZP, yessotoxin and palytoxin produced by dinoflagellates as well as their molecular mechanisms of action on voltage-gated ion channels.

2.

Gene_expression (produced) of PSP in PSP associated with shellfish poisoning and poisoning
5) Confidence 0.11 Published 2008 Journal Marine Drugs Section Body Doc Link PMC2525493 Disease Relevance 1.57 Pain Relevance 0.07
Throughout this evaluation of abalone PSP, toxicity was tested using the AOAC mouse bioassay with levels reported from below the limit of detection to greater than 1600 ?
Gene_expression (evaluation) of PSP in PSP associated with toxicity and shellfish poisoning
6) Confidence 0.06 Published 2008 Journal Marine Drugs Section Body Doc Link PMC2525492 Disease Relevance 0.63 Pain Relevance 0
Most humans who experience PSP have consumed toxic bivalves [84], but occasionally, non traditional vectors such as toxic gastropods and crustaceans [85], and rarely toxic fish [52, 100] are implicated (see section 3).
Gene_expression (experience) of PSP in section 3 associated with shellfish poisoning
7) Confidence 0.06 Published 2008 Journal Marine Drugs Section Body Doc Link PMC2525492 Disease Relevance 1.11 Pain Relevance 0.08

General Comments

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