INT24358

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Context Info
Confidence 0.36
First Reported 1984
Last Reported 2005
Negated 0
Speculated 0
Reported most in Abstract
Documents 3
Total Number 3
Disease Relevance 0.35
Pain Relevance 1.67

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Slc12a3) transport (Slc12a3) plasma membrane (Slc12a3)
transmembrane transport (Slc12a3)
Anatomy Link Frequency
Spinal 1
brain 1
TSC 1
Slc12a3 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Neuropeptide 7 99.98 Very High Very High Very High
opiate 3 96.92 Very High Very High Very High
antagonist 4 96.64 Very High Very High Very High
Clonidine 5 94.48 High High
Spinal cord 2 93.84 High High
agonist 4 90.48 High High
Opioid 3 86.40 High High
Neurotransmitter 1 75.00 Quite High
medulla 1 65.44 Quite High
Calcitonin gene-related peptide 1 61.60 Quite High
Disease Link Frequency Relevance Heat
Hypertension 3 97.88 Very High Very High Very High
Sprains And Strains 2 90.24 High High
Neurocysticercosis 5 50.00 Quite Low
Arachnoiditis 2 5.00 Very Low Very Low Very Low
Parasitic Infection 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
These findings suggest that the reduced neuropeptide concentrations of the SHR (particularly those within the CSC) and TSC may be a result of, rather than a causal factor in, hypertension.
TSC Binding (concentrations) of in TSC associated with hypertension and neuropeptide
1) Confidence 0.36 Published 1987 Journal J. Cardiovasc. Pharmacol. Section Abstract Doc Link 2455167 Disease Relevance 0.35 Pain Relevance 0.87
CONCLUSIONS: Spinal racemose NCC associated to arachnoiditis has a poor prognosis and is often untreatable.
NCC Binding (associated) of in Spinal
2) Confidence 0.24 Published 2005 Journal Rev Neurol Section Body Doc Link 15898016 Disease Relevance 0 Pain Relevance 0
The present results furnish an explanation for our previous findings, i.e. good yield of binding to (digitonin/NaCl) solubilized binding sites from rat brain can only be obtained with labeled opiate antagonists.
NaCl Binding (binding) of in brain associated with antagonist and opiate
3) Confidence 0.09 Published 1984 Journal Brain Res. Section Abstract Doc Link 6320961 Disease Relevance 0 Pain Relevance 0.80

General Comments

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