INT243619

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Context Info
Confidence 0.08
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.43
Pain Relevance 0.36

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (Nfatc1) DNA binding (Nfatc1) cytoplasm (Nfatc1)
Anatomy Link Frequency
Th1 cells 2
Nfatc1 (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 41 92.16 High High
cytokine 23 88.00 High High
chemokine 4 86.60 High High
Arthritis 15 58.96 Quite High
Crohn's disease 7 5.00 Very Low Very Low Very Low
rheumatoid arthritis 4 5.00 Very Low Very Low Very Low
Inflammatory response 1 5.00 Very Low Very Low Very Low
spinal inflammation 1 5.00 Very Low Very Low Very Low
antagonist 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 42 92.16 High High
Hypersensitivity 14 72.72 Quite High
Arthritis 13 58.96 Quite High
Severe Combined Immunodeficiency 4 52.32 Quite High
Hyperplasia 4 20.08 Low Low
Disease 14 5.00 Very Low Very Low Very Low
Inflammatory Bowel Disease 8 5.00 Very Low Very Low Very Low
Rheumatoid Arthritis 6 5.00 Very Low Very Low Very Low
Seronegative Spondarthritis 2 5.00 Very Low Very Low Very Low
Rheumatic Diseases 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Twist1 in Th1 cells thus acts as an endogenous regulator limiting the proinflammatory potential of Th1 cells in the continuous presence of antigen, i.e., repeated activation of NFAT and NF-?
Negative_regulation (repeated) of Positive_regulation (activation) of NFAT in Th1 cells
1) Confidence 0.08 Published 2008 Journal The Journal of Experimental Medicine Section Body Doc Link PMC2525589 Disease Relevance 0.43 Pain Relevance 0.36

General Comments

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