INT243652

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Context Info
Confidence 0.01
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0.09

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (Gk, Il12a) extracellular space (Il12a) mitochondrion (Gk)
extracellular region (Il12a) histone binding (Gk) nucleus (Gk)
Anatomy Link Frequency
accessory cells 2
Gk (Rattus norvegicus)
Il12a (Rattus norvegicus)
Pain Link Frequency Relevance Heat
cytokine 23 65.68 Quite High
Potency 2 56.16 Quite High
Inflammation 13 5.00 Very Low Very Low Very Low
Spinal cord 12 5.00 Very Low Very Low Very Low
Multiple sclerosis 11 5.00 Very Low Very Low Very Low
rheumatoid arthritis 5 5.00 Very Low Very Low Very Low
Arthritis 4 5.00 Very Low Very Low Very Low
dexamethasone 2 5.00 Very Low Very Low Very Low
Central nervous system 1 5.00 Very Low Very Low Very Low
cINOD 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Asthma 2 27.68 Quite Low
Multiple Sclerosis 17 5.00 Very Low Very Low Very Low
INFLAMMATION 13 5.00 Very Low Very Low Very Low
Autoimmune Disease 13 5.00 Very Low Very Low Very Low
Inflammatory Bowel Disease 7 5.00 Very Low Very Low Very Low
Disease 5 5.00 Very Low Very Low Very Low
Rheumatoid Arthritis 5 5.00 Very Low Very Low Very Low
Experimental Arthritis 4 5.00 Very Low Very Low Very Low
Leukemia 3 5.00 Very Low Very Low Very Low
Sprains And Strains 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
inhibition, and although it was convincingly demonstrated that GK inhibit the production of IL-12, necessary for Th1 differentiation [12,24], it is tempting to speculate that additional influence through modulation of expression of molecules in accessory cells have minor contribution, if any.
GK Negative_regulation (inhibit) of Gene_expression (production) of IL-12 in accessory cells
1) Confidence 0.01 Published 2008 Journal BMC Immunol Section Body Doc Link PMC2525626 Disease Relevance 0 Pain Relevance 0.09

General Comments

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