INT24366

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Context Info
Confidence 0.50
First Reported 1987
Last Reported 2011
Negated 0
Speculated 0
Reported most in Body
Documents 4
Total Number 5
Disease Relevance 4.01
Pain Relevance 3.79

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell proliferation (NPY) extracellular space (NPY) extracellular region (NPY)
cell (NPY)
Anatomy Link Frequency
cardiomyocyte 4
nerve 2
adrenal medulla 2
NPY (Homo sapiens)
Pain Link Frequency Relevance Heat
Neuropeptide 247 100.00 Very High Very High Very High
Enkephalin 54 100.00 Very High Very High Very High
noradrenaline 7 100.00 Very High Very High Very High
medulla 12 98.28 Very High Very High Very High
Neurotransmitter 32 97.28 Very High Very High Very High
Catecholamine 10 96.56 Very High Very High Very High
Pain 17 96.08 Very High Very High Very High
antagonist 9 93.52 High High
substance P 2 92.96 High High
Desipramine 1 92.00 High High
Disease Link Frequency Relevance Heat
Stress 96 99.98 Very High Very High Very High
Apoptosis 4 99.80 Very High Very High Very High
Left Ventricular Hypertrophy 4 96.16 Very High Very High Very High
Pain 28 96.08 Very High Very High Very High
Increased Venous Pressure Under Development 14 93.68 High High
Heart Failure 86 92.80 High High
Urological Neuroanatomy 2 82.44 Quite High
Pressure And Volume Under Development 14 80.32 Quite High
INFLAMMATION 14 73.44 Quite High
Syndrome 88 73.40 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The nerve-evoked NPY release that is enhanced after reserpine treatment is related to remaining vasoconstrictor effects.
Positive_regulation (enhanced) of Localization (release) of NPY in nerve
1) Confidence 0.50 Published 1987 Journal J. Cardiovasc. Pharmacol. Section Abstract Doc Link 2455193 Disease Relevance 0.29 Pain Relevance 0.65
SNS activation leads to increased cardiomyocyte apoptosis [40] and increases the release of the neurohormone Neuropeptide Y (NPY).
Positive_regulation (increases) of Localization (release) of NPY in cardiomyocyte associated with neuropeptide and apoptosis
2) Confidence 0.33 Published 2011 Journal International Journal of Nephrology Section Body Doc Link PMC3021842 Disease Relevance 1.19 Pain Relevance 0.19
SNS activation leads to increased cardiomyocyte apoptosis [40] and increases the release of the neurohormone Neuropeptide Y (NPY).
Positive_regulation (increases) of Localization (release) of neurohormone Neuropeptide Y in cardiomyocyte associated with neuropeptide and apoptosis
3) Confidence 0.33 Published 2011 Journal International Journal of Nephrology Section Body Doc Link PMC3021842 Disease Relevance 1.19 Pain Relevance 0.19
Stress induces the secretion of enkephalins, catestatin, NPY, VIP, galanin, and other neuropeptides (23–26).
Positive_regulation (induces) of Localization (secretion) of NPY associated with stress, neuropeptide and enkephalin
4) Confidence 0.23 Published 2010 Journal AAPS J Section Body Doc Link PMC2976990 Disease Relevance 1.05 Pain Relevance 2.49
During an antecedent event, activation of the SAS system (locus coerulus/norepinephrine/sympathetic nervous system) evokes the release of noradrenaline and neuropeptide-Y from postganglionic nerve terminals, while preganglionic innervation of the adrenal medulla results in an increased secretion of adrenaline and dihydroxyphenylaline (DOPA) [50].
Positive_regulation (evokes) of Localization (release) of neuropeptide-Y in adrenal medulla associated with medulla, neuropeptide and noradrenaline
5) Confidence 0.03 Published 2006 Journal Chiropr Osteopat Section Body Doc Link PMC1629015 Disease Relevance 0.29 Pain Relevance 0.27

General Comments

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