INT243671

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Context Info
Confidence 0.00
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0.05
Pain Relevance 0.14

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Il6) aging (Il6) extracellular region (Il6)
Anatomy Link Frequency
T cells 4
Mp (Mus musculus)
Il6 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
cytokine 46 97.84 Very High Very High Very High
Potency 4 30.72 Quite Low
Spinal cord 24 20.68 Low Low
Inflammation 26 5.00 Very Low Very Low Very Low
Multiple sclerosis 22 5.00 Very Low Very Low Very Low
rheumatoid arthritis 10 5.00 Very Low Very Low Very Low
Arthritis 8 5.00 Very Low Very Low Very Low
dexamethasone 4 5.00 Very Low Very Low Very Low
Central nervous system 2 5.00 Very Low Very Low Very Low
cINOD 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Asthma 4 52.12 Quite High
Disease 10 12.20 Low Low
Multiple Sclerosis 34 9.68 Low Low
INFLAMMATION 26 5.00 Very Low Very Low Very Low
Autoimmune Disease 26 5.00 Very Low Very Low Very Low
Inflammatory Bowel Disease 14 5.00 Very Low Very Low Very Low
Rheumatoid Arthritis 10 5.00 Very Low Very Low Very Low
Experimental Arthritis 8 5.00 Very Low Very Low Very Low
Leukemia 6 5.00 Very Low Very Low Very Low
Sprains And Strains 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In line with these data, we demonstrated that MP inhibited IL-6 production in LNC population devoid of T lymphocytes.
MP Negative_regulation (inhibited) of Gene_expression (production) of IL-6 in T lymphocytes
1) Confidence 0.00 Published 2008 Journal BMC Immunol Section Body Doc Link PMC2525626 Disease Relevance 0.05 Pain Relevance 0.09
As a result it was shown that MP potently inhibited IL-6 production in LPS-stimulated CD3- cells, thus suggesting that indirect influence of MP on IL-17 production could be, at least partly, conducted through inhibition of IL-6 production by non-T cells.


MP Negative_regulation (inhibited) of Gene_expression (production) of IL-6 in T cells
2) Confidence 0.00 Published 2008 Journal BMC Immunol Section Body Doc Link PMC2525626 Disease Relevance 0 Pain Relevance 0.05

General Comments

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