INT243693

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Context Info
Confidence 0.27
First Reported 2008
Last Reported 2008
Negated 1
Speculated 0
Reported most in Body
Documents 1
Total Number 3
Disease Relevance 0.64
Pain Relevance 0.79

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transport (NDUFA2) mitochondrion (NDUFA2) small molecule metabolic process (NDUFA2)
NDUFA2 (Homo sapiens)
Pain Link Frequency Relevance Heat
aspirin 144 99.92 Very High Very High Very High
Inflammation 90 96.48 Very High Very High Very High
cytokine 33 82.24 Quite High
Arthritis 12 52.88 Quite High
Crohn's disease 3 52.00 Quite High
rheumatoid arthritis 3 43.12 Quite Low
Pain 6 29.36 Quite Low
Kinase C 3 8.00 Low Low
cINOD 18 5.00 Very Low Very Low Very Low
dexamethasone 15 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 93 96.48 Very High Very High Very High
Death 9 82.16 Quite High
Disease 6 53.68 Quite High
Arthritis 18 52.88 Quite High
Asthma 3 50.40 Quite High
Rheumatoid Arthritis 3 43.12 Quite Low
Autoimmune Disease 3 39.36 Quite Low
Pain 6 29.36 Quite Low
Atherosclerosis 9 5.00 Very Low Very Low Very Low
Necrosis 6 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
release by B8.
Localization (release) of B8
1) Confidence 0.27 Published 2008 Journal J Inflamm (Lond) Section Body Doc Link PMC2525633 Disease Relevance 0.33 Pain Relevance 0.22
However, as this effect is not mimicked by the NO-donor, DEA/NO, it is apparently a specific property of B8 that is possibly related to amount, duration or site of NO release.
Neg (NO) Localization (release) of B8
2) Confidence 0.27 Published 2008 Journal J Inflamm (Lond) Section Body Doc Link PMC2525633 Disease Relevance 0.08 Pain Relevance 0.19
We have previously shown that the furoxan-aspirin B7 releases significantly less NO than B8 [19] and thus suggest that the NO release from B7 is insufficient to result in an anti-inflammatory effect similar to that of B8.
Localization (releases) of B8 associated with aspirin and inflammation
3) Confidence 0.25 Published 2008 Journal J Inflamm (Lond) Section Body Doc Link PMC2525633 Disease Relevance 0.23 Pain Relevance 0.37

General Comments

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