INT243790

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Context Info
Confidence 0.28
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 2
Disease Relevance 0.23
Pain Relevance 0.35

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell morphogenesis (MSX1) nucleus (MSX1)
Anatomy Link Frequency
midbrain 2
MSX1 (Homo sapiens)
Pain Link Frequency Relevance Heat
midbrain 22 100.00 Very High Very High Very High
Central nervous system 2 75.92 Quite High
Substantia nigra 18 5.00 Very Low Very Low Very Low
Dopamine 6 5.00 Very Low Very Low Very Low
monoamine 4 5.00 Very Low Very Low Very Low
Nerve growth factor 2 5.00 Very Low Very Low Very Low
Neuritis 2 5.00 Very Low Very Low Very Low
Glutamate 2 5.00 Very Low Very Low Very Low
Ventral tegmentum 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Death 30 88.56 High High
Apoptosis 18 88.12 High High
Disease 12 5.00 Very Low Very Low Very Low
Mucocutaneous Lymph Node Syndrome 6 5.00 Very Low Very Low Very Low
Neuritis 2 5.00 Very Low Very Low Very Low
Reprotox - General 1 2 5.00 Very Low Very Low Very Low
Hypokinesia 2 5.00 Very Low Very Low Very Low
Repression 2 5.00 Very Low Very Low Very Low
Targeted Disruption 2 5.00 Very Low Very Low Very Low
Tremor 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Cultures expressed the midbrain dopaminergic markers, PITX3, En1, TH, Msx1, and Aldh1 (Figures 2D–2H), supporting the notion that hESC-derived cells were committed to a midbrain dopaminergic phenotype.
Gene_expression (expressed) of Msx1 in midbrain associated with midbrain
1) Confidence 0.28 Published 2007 Journal Frontiers in Neuroanatomy Section Body Doc Link PMC2525922 Disease Relevance 0.18 Pain Relevance 0.13
The cultured cells also expressed other midbrain dopaminergic markers (PITX3, En1, Msx1, and Aldh1), suggesting that some had differentiated into midbrain dopaminergic neurons.
Gene_expression (expressed) of Msx1 in midbrain associated with midbrain
2) Confidence 0.28 Published 2007 Journal Frontiers in Neuroanatomy Section Abstract Doc Link PMC2525922 Disease Relevance 0.06 Pain Relevance 0.21

General Comments

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