INT243883

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Context Info
Confidence 0.19
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.07
Pain Relevance 0.15

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (DLG4) plasma membrane (DLG4) protein complex assembly (DLG4)
Anatomy Link Frequency
synapses 1
DLG4 (Homo sapiens)
Pain Link Frequency Relevance Heat
GABAergic 16 98.28 Very High Very High Very High
Glutamate receptor 10 88.16 High High
Neurotransmitter 9 5.00 Very Low Very Low Very Low
hyperexcitability 4 5.00 Very Low Very Low Very Low
nMDA receptor 4 5.00 Very Low Very Low Very Low
Glutamate 3 5.00 Very Low Very Low Very Low
long-term potentiation 2 5.00 Very Low Very Low Very Low
gABA 2 5.00 Very Low Very Low Very Low
depression 2 5.00 Very Low Very Low Very Low
Endocannabinoid 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Adhesions 3 66.12 Quite High
Disease 6 50.00 Quite Low
Epilepsy 7 11.24 Low Low
Neurological Disease 7 5.00 Very Low Very Low Very Low
Intellectual Impairment 6 5.00 Very Low Very Low Very Low
Autism 5 5.00 Very Low Very Low Very Low
Schizophrenia 2 5.00 Very Low Very Low Very Low
Depression 2 5.00 Very Low Very Low Very Low
Convulsion 2 5.00 Very Low Very Low Very Low
Encephalopathy 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Likewise, knockdown of PSD-95 results in partial loss of excitatory synapses, which decreases the E-I ratio of synaptic input (Prange et al., 2004).
Negative_regulation (knockdown) of PSD-95 in synapses
1) Confidence 0.19 Published 2008 Journal Frontiers in Molecular Neuroscience Section Body Doc Link PMC2526001 Disease Relevance 0.07 Pain Relevance 0.15

General Comments

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